Effects of Optical Zone Variation of High-Addition Multifocal Contact Lenses on the Global Flash Multifocal Electroretinography.

IF 2 4区医学 Q2 OPHTHALMOLOGY

Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-05-16 DOI:10.1097/ICL.0000000000001099

Laurence Boily, Langis Michaud, Marie-Lou Garon, Rémy Marcotte

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引用次数: 0

Abstract

Objectives: To evaluate the retinal response to myopic defocus after the wear of soft multifocal contact lenses with high addition through electroretinography.

Methods: Twenty-seven participants meeting inclusion criteria were enrolled. Tropicamide 1% drops (2) were instilled. Participants were then fitted with three different contact lenses: a single-vision spherical lens (SE +3.00 D), L1, serving as a control, and two soft multifocal lens designs (SE +3.00 D/add +10 D), one with a central distance zone of 4.0 mm (L2) and one with a central distance zone of 7.0 mm (L3). A global flash multifocal electroretinography was performed. Direct component (DC) amplitude, DC peak time, induced component (IC) amplitude, and IC peak time were recorded. Waveforms were grouped into five concentric areas, covering from 0° to 24° of retinal eccentricity. Differences of L2/L3 versus L1 were analyzed with t tests. Finally, correlations were calculated between the percentage of defocus in the pupil area versus the electroretinography results.

Results: Results show that the DC amplitude, caused mainly by photoreceptors and bipolar cells, is not influenced by the design of the lenses. The IC amplitude, however, is significantly decreased when the lens with a smaller optical zone (L2) is worn. This significant difference only concerns the ring 5, which corresponds to a retinal eccentricity of 15.7° to 24.0°.

Conclusion: Soft multifocal lens designs influence the peripheral retinal reaction to defocus. A larger treatment zone seems to significantly impact the retinal response to defocus between 15.7° and 24.0° of eccentricity from the macula.

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高倍多焦距隐形眼镜的光学区域变化对全球闪光多焦距视网膜成像的影响。

目的通过视网膜电图评估配戴高倍软性多焦点隐形眼镜后视网膜对近视散焦的反应：纳入符合纳入标准的 27 名参与者。滴入 1%托吡卡胺滴眼液 (2)。然后为参试者配戴三种不同的隐形眼镜：单视力球面镜（SE +3.00 D），L1，作为对照；两种软性多焦点镜片设计（SE +3.00 D/ Addd +10 D），一种中央距离区为 4.0 mm（L2），另一种中央距离区为 7.0 mm（L3）。进行了全球闪烁多焦视网膜电图检查。记录了直接成分（DC）振幅、DC 峰值时间、诱导成分（IC）振幅和 IC 峰值时间。波形被分为五个同心区域，涵盖视网膜偏心率 0° 至 24°。用 t 检验分析 L2/L3 与 L1 的差异。最后，计算了瞳孔区散焦百分比与视网膜电图结果之间的相关性：结果显示，主要由感光细胞和双极细胞引起的直流电振幅不受镜片设计的影响。然而，当佩戴光学区（L2）较小的镜片时，IC 振幅会明显下降。这一显著差异仅涉及环 5，对应视网膜偏心 15.7° 至 24.0°：结论：软性多焦点镜片的设计会影响周边视网膜对散焦的反应。在黄斑偏心率为 15.7°至 24.0°之间，较大的治疗区似乎会明显影响视网膜对散焦的反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eye & Contact Lens-Science and Clinical Practice OPHTHALMOLOGY-

CiteScore

4.50

自引率

4.30%

发文量

150

审稿时长

6-12 weeks

期刊介绍： Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.