Risk factors associated with COVID-19 mortality in Mexico.

IF 0.6 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Gaceta medica de Mexico Pub Date : 2024-01-01 DOI:10.24875/GMM.M24000844

Anna Fomina, Antonio Villa-Romero, Guadalupe S García de la Torre, Laura Leticia Tirado, Rosa M Wong-Chew

{"title":"Risk factors associated with COVID-19 mortality in Mexico.","authors":"Anna Fomina, Antonio Villa-Romero, Guadalupe S García de la Torre, Laura Leticia Tirado, Rosa M Wong-Chew","doi":"10.24875/GMM.M24000844","DOIUrl":null,"url":null,"abstract":"Background: On December 31, 2019, one of the most serious pandemics in recent times made its appearance. Certain health conditions, such as obesity and diabetes mellitus, have been described to be related to COVID-19 unfavorable outcomes.Objective: To identify factors associated with mortality in patients with COVID-19.Material and methods: Retrospective cohort of 998,639 patients. Patient sociodemographic and clinical characteristics were analyzed, with survivors being compared with the deceased individuals. Cox proportional hazards model was used to identify variables predictive of COVID-19-associated mortality.Results: Among the deceased patients, men accounted for 64.3%, and women, for 35.7%, with the difference being statistically significant. Subjects older than 80 years had a 13-fold higher risk of dying from COVID-19 (95% CI = 12,469, 13,586), while chronic kidney disease entailed a risk 1.5 times higher (95% CI = 1,341, 1,798), and diabetes mellitus involved a risk 1.25 times higher (95% CI = 1.238,1.276).Conclusions: Age, sex, diabetes mellitus and obesity were found to be predictors of COVID-19 mortality. Further research related to chronic obstructive pulmonary disease, cardiovascular diseases, smoking and pregnancy is suggested.","PeriodicalId":12736,"journal":{"name":"Gaceta medica de Mexico","volume":"160 1","pages":"9-16"},"PeriodicalIF":0.6000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gaceta medica de Mexico","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.24875/GMM.M24000844","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background: On December 31, 2019, one of the most serious pandemics in recent times made its appearance. Certain health conditions, such as obesity and diabetes mellitus, have been described to be related to COVID-19 unfavorable outcomes.

Objective: To identify factors associated with mortality in patients with COVID-19.

Material and methods: Retrospective cohort of 998,639 patients. Patient sociodemographic and clinical characteristics were analyzed, with survivors being compared with the deceased individuals. Cox proportional hazards model was used to identify variables predictive of COVID-19-associated mortality.

Results: Among the deceased patients, men accounted for 64.3%, and women, for 35.7%, with the difference being statistically significant. Subjects older than 80 years had a 13-fold higher risk of dying from COVID-19 (95% CI = 12,469, 13,586), while chronic kidney disease entailed a risk 1.5 times higher (95% CI = 1,341, 1,798), and diabetes mellitus involved a risk 1.25 times higher (95% CI = 1.238,1.276).

Conclusions: Age, sex, diabetes mellitus and obesity were found to be predictors of COVID-19 mortality. Further research related to chronic obstructive pulmonary disease, cardiovascular diseases, smoking and pregnancy is suggested.

查看原文本刊更多论文

墨西哥 COVID-19 死亡率的相关风险因素。

背景：2019年12月31日，近代最严重的流行病之一登场。据描述，某些健康状况，如肥胖和糖尿病，与 COVID-19 的不利结局有关：目的：确定与 COVID-19 患者死亡率相关的因素：材料和方法：998 639 例患者的回顾性队列。分析了患者的社会人口学和临床特征，并将存活者与死亡者进行了比较。采用 Cox 比例危险模型确定可预测 COVID-19 相关死亡率的变量：结果：在死亡患者中，男性占 64.3%，女性占 35.7%，差异具有统计学意义。年龄超过80岁的受试者死于COVID-19的风险高出13倍（95% CI = 12,469, 13,586），而慢性肾病导致的风险高出1.5倍（95% CI = 1,341, 1,798），糖尿病导致的风险高出1.25倍（95% CI = 1.238, 1.276）：结论：年龄、性别、糖尿病和肥胖是COVID-19死亡率的预测因素。建议进一步开展与慢性阻塞性肺病、心血管疾病、吸烟和妊娠有关的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Gaceta medica de Mexico 医学-医学：内科

CiteScore

1.00

自引率

0.00%

发文量

216

审稿时长

6-12 weeks

期刊介绍： Gaceta Médica de México México is the official scientific journal of the Academia Nacional de Medicina de México, A.C. Its goal is to contribute to health professionals by publishing the most relevant progress both in research and clinical practice. Gaceta Médica de México is a bimonthly peer reviewed journal, published both in paper and online in open access, both in Spanish and English. It has a brilliant editorial board formed by national and international experts.