Longitudinal associations between subjective cognitive impairment, pain and depressive symptoms in home-dwelling older adults: Modelling within-person effects

IF 3.6 3区医学 Q2 GERIATRICS & GERONTOLOGY

International Journal of Geriatric Psychiatry Pub Date : 2024-05-18 DOI:10.1002/gps.6103

Miharu Nakanishi, Marieke Perry, Rachele Bejjani, Satoshi Yamaguchi, Satoshi Usami, Jenny T. van der Steen

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引用次数: 0

Abstract

Objectives

Cognitive impairment, pain and depressive symptoms are common and interrelated factors in older adults. However, the directionality and specificity of their association remains unclarified. This study explored whether these factors prospectively increase reciprocal risk and examined the longitudinal association between these factors and quality of life (QoL).

Methods

This study used longitudinal data from The Older Persons and Informal Caregivers Survey Minimal Data Set (TOPICS-MDS; the Netherlands). Older adults self-reported cognitive impairment, pain, depressive symptoms and QoL at baseline and after 6 and 12 months of follow-up. The Random Intercept Cross-Lagged Panel Model was used to assess the prospective association between the three factors, while a multilevel linear regression analysis in a two-level random intercept model was used to examine the longitudinal associations between the three factors and QoL at the within-person level.

Results

The data of 11,582 home-dwelling older adults with or without subjective cognitive impairment were analysed. At the within-person level, pain at 6 months was associated with subsequent depressive symptoms (β = 0.04, p = 0.024). The reverse association from depression to pain, and longitudinal associations between pain and subjective cognitive impairment and between depressive symptoms and subjective cognitive impairment were non-significant. Pain, depressive symptoms and subjective cognitive impairment showed a significant association with poor QoL 6 months later.

Conclusions

A directional relationship was observed from pain to depressive symptoms. Pain reduction holds a potential benefit in the prevention of depressive symptoms, ultimately optimising the QoL of older adults.

Abstract Image

查看原文本刊更多论文

居家老年人主观认知障碍、疼痛和抑郁症状之间的纵向联系：模拟人内效应。

目的：认知障碍、疼痛和抑郁症状是老年人常见且相互关联的因素。然而，它们之间关联的方向性和特异性仍不明确。本研究探讨了这些因素是否会前瞻性地增加相互风险，并研究了这些因素与生活质量（QoL）之间的纵向联系：本研究使用了老年人和非正式照顾者调查最小数据集（TOPICS-MDS，荷兰）中的纵向数据。老年人在基线以及随访 6 个月和 12 个月后对认知障碍、疼痛、抑郁症状和 QoL 进行了自我报告。随机截距交叉滞后面板模型用于评估这三个因素之间的前瞻性关联，而两级随机截距模型中的多级线性回归分析则用于研究这三个因素和 QoL 在个人层面上的纵向关联：分析了 11,582 名有或没有主观认知障碍的居家老年人的数据。在个人层面上，6 个月时的疼痛与随后出现的抑郁症状相关（β = 0.04，p = 0.024）。抑郁与疼痛之间的反向关联、疼痛与主观认知障碍之间的纵向关联以及抑郁症状与主观认知障碍之间的纵向关联均不显著。疼痛、抑郁症状和主观认知障碍与 6 个月后的不良 QoL 有显著关联：从疼痛到抑郁症状之间存在定向关系。减轻疼痛对预防抑郁症状有潜在的益处，最终可优化老年人的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Geriatric Psychiatry 医学-精神病学

CiteScore

6.10

自引率

2.50%

发文量

168

审稿时长

4-8 weeks

期刊介绍： The rapidly increasing world population of aged people has led to a growing need to focus attention on the problems of mental disorder in late life. The aim of the Journal is to communicate the results of original research in the causes, treatment and care of all forms of mental disorder which affect the elderly. The Journal is of interest to psychiatrists, psychologists, social scientists, nurses and others engaged in therapeutic professions, together with general neurobiological researchers. The Journal provides an international perspective on the important issue of geriatric psychiatry, and contributions are published from countries throughout the world. Topics covered include epidemiology of mental disorders in old age, clinical aetiological research, post-mortem pathological and neurochemical studies, treatment trials and evaluation of geriatric psychiatry services.