Bone Metastases.

IF 2.6 4区 医学 Q3 ONCOLOGY
Gary J R Cook, Matthew P Thorpe
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引用次数: 0

Abstract

Abstract: Bone metastases occur frequently in common malignancies such as breast and prostate cancer. They are responsible for considerable morbidity and skeletal-related events. Fortunately, there are now several systemic, focal, and targeted therapies that can improve quality and length of life, including radionuclide therapies. It is therefore important that bone metastases can be detected as early as possible and that treatment can be accurately and sensitively monitored. Several bone-specific and tumor-specific single-photon emission computed tomography and positron emission tomography molecular imaging agents are available, for detection and monitoring response to systemic therapeutics, as well as theranostic agents to confirm target expression and predict response to radionuclide therapies.

骨转移。
摘要:骨转移经常发生在乳腺癌和前列腺癌等常见恶性肿瘤中。骨转移瘤会导致相当高的发病率和与骨骼相关的事件。幸运的是,现在有几种全身、病灶和靶向疗法,包括放射性核素疗法,可以改善生活质量和延长生命。因此,尽早发现骨转移灶并对治疗进行准确、灵敏的监测非常重要。目前已有几种骨特异性和肿瘤特异性单光子发射计算机断层扫描和正电子发射断层扫描分子成像剂,用于检测和监测对全身治疗的反应,以及用于确认靶点表达和预测对放射性核素疗法反应的治疗药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer journal
Cancer journal 医学-肿瘤学
CiteScore
3.90
自引率
0.00%
发文量
102
审稿时长
7.5 months
期刊介绍: The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.
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