Teaching an Old Dog New Tricks for Achieving CB2-Selective Inverse Agonism

IF 12.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

ACS Central Science Pub Date : 2024-05-08 DOI:10.1021/acscentsci.4c00673

Morgane Mando, Christopher W. Cunningham and Alexander J. Grenning,

引用次数: 0

Abstract

Three laboratories team up to “flip the switch” and turn a CB₂R agonist into a fluorescent CB₂R inverse agonist.

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教老狗学新招，实现 CB2 选择性反向激动作用

三个实验室联手 "打开开关"，将 CB2R 激动剂变成了荧光 CB2R 反向激动剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Central Science Chemical Engineering-General Chemical Engineering

CiteScore

25.50

自引率

0.50%

发文量

194

审稿时长

10 weeks

期刊介绍： ACS Central Science publishes significant primary reports on research in chemistry and allied fields where chemical approaches are pivotal. As the first fully open-access journal by the American Chemical Society, it covers compelling and important contributions to the broad chemistry and scientific community. "Central science," a term popularized nearly 40 years ago, emphasizes chemistry's central role in connecting physical and life sciences, and fundamental sciences with applied disciplines like medicine and engineering. The journal focuses on exceptional quality articles, addressing advances in fundamental chemistry and interdisciplinary research.