Change in Chromatographic Parameters of Some Phenylpropanoids in Different Mobile Phases Under Reversed-Phase HPLC Conditions

IF 0.8 4区医学 Q4 CHEMISTRY, MEDICINAL

Pharmaceutical Chemistry Journal Pub Date : 2024-05-13 DOI:10.1007/s11094-024-03128-8

O. K. Abramov, A. F. Ryabukha, I. V. Pletneva

引用次数: 0

Abstract

The effect of the eluent composition (type and concentration of the organic and acid components) on the retention times and selectivity of the separation of some standard samples of phenylpropanoids under reversed- phase HPLC conditions is studied. Ethanol, being a nontoxic solvent, exhibited good characteristics as an eluent for the separation of this group of substances. A mobile phase containing ethanol and organic acids could be recommended as an extractant for studies of plant raw material containing phenylpropanoids.

Abstract Image

查看原文本刊更多论文

反相高效液相色谱条件下不同流动相中某些苯丙酸类化合物色谱参数的变化

研究了在反相高效液相色谱条件下，洗脱剂成分（有机成分和酸性成分的类型和浓度）对一些苯丙类标准样品的保留时间和分离选择性的影响。乙醇作为一种无毒溶剂，在作为洗脱液分离这类物质时表现出良好的特性。含有乙醇和有机酸的流动相可作为萃取剂，用于含有苯丙烷的植物原料的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pharmaceutical Chemistry Journal CHEMISTRY, MEDICINAL-PHARMACOLOGY & PHARMACY

CiteScore

1.30

自引率

22.20%

发文量

226

审稿时长

3-8 weeks

期刊介绍： Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including: methods of synthesis; results of pharmacological, toxicological, and biochemical studies; investigation of structure - activity relationships in prediction of new compounds; methods and technical facilities used; and problems associated with the development of ecologically safe and economically feasible methods of industrial production. In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world. Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April. All articles are peer-reviewed.