Preparation of Pt-doped hydroxyapatite via wet co-precipitation method

Abstract

Doping of Hydroxyapatite (HA) with foreign ions is known as a chemical approach to improve its physicochemical characteristics and expand its biomedical applications. In the current paper, Pt-doped HA (Pt-HA) was synthesized by the co-precipitation method, and the product was characterized using conventional techniques. The XRD analysis results show that the as-synthesized Pt-HA powder exhibits apatite characteristics with lower degrees of crystallinity compared to pure hydroxyapatite, and no new phase or impurity is found. The SEM observations suggest the plate-shaped particles with homogeneous surfaces in which doping of hydroxyapatite with Pt ions led to a decrease in the length of HA particles. The EDS analysis highlighted the purity of the samples and confirmed the presence of Ca, P, O, and Pt elements in the Pt-HA sample. FTIR spectroscopy revealed the presence of the various vibrational modes corresponding to PO₄³⁻, OH⁻ and CO₃²⁻ functional groups. The mean particle size measurement of the as-prepared HA and Pt-HA samples, using the dynamic Light Scattering (DLS) analysis confirmed a decrease in particle size in the Pt-doped HA sample compared to pure HA. TGA results indicated that the prepared Pt-doped HA sample has good thermal stability.