Peri-implant diseases and systemic inflammation: A preliminary analysis from a cross-sectional survey of patients with hypertension

IF 4.2 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Marco Orlandi, Nicola Pranno, Vipul Patel, Piero Papi, Bianca Di Murro, Giorgio Pompa, Antonella Polimeni, Claudio Letizia, Jeanie Suvan, Francesco D'Aiuto
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引用次数: 0

Abstract

Background

The aim of this study was to investigate the association between peri-implant diseases and systemic inflammation assessed by serum C-reactive protein (CRP) levels in a sample of patients with hypertension.

Methods

A total of 151 participants with hypertension were included in a cross-sectional study. The population was divided into six groups according to their peri-implant and periodontal status (healthy controls, mucositis, peri-implantitis, periodontitis, periodontitis and mucositis, periodontitis, and peri-implantitis). Linear, logistic regression, and correlation analyses were performed.

Results

CRP levels were statistically significantly higher in participants with periodontitis alone (median 3.2 mg/L, interquartile range [IQR] 1.8, p = 0.012), combined with mucositis (3.10 mg/L, IQR 2.35, p < 0.001) or peri-implantitis (2.7 mg/L, IQR 2.53, p = 0.002) when compared to the healthy controls (1 mg/L, IQR 1.2). This association was independent of age, sex, smoking status, and adiposity differences. Participants with periodontitis with and without peri-implant diseases had the greatest odds of exhibiting CRP > 3 mg/L (odds ratio = 7.3, 95% confidence interval 1.6–33.9).

Conclusions

Peri-implant diseases are associated with systemic inflammation, but the nature of the association should be further investigated.

Abstract Image

种植体周围疾病与全身炎症:对高血压患者横断面调查的初步分析。
背景:本研究旨在调查高血压患者血清C反应蛋白(CRP)水平评估的种植体周围疾病与全身炎症之间的关系:本研究旨在调查高血压患者样本中种植体周围疾病与通过血清C反应蛋白(CRP)水平评估的全身炎症之间的关系:一项横断面研究共纳入了 151 名高血压患者。根据种植体周围和牙周状况(健康对照组、粘膜炎组、种植体周围炎组、牙周炎组、牙周炎和粘膜炎组、牙周炎组和种植体周围炎组)将人群分为六组。进行了线性、逻辑回归和相关分析:仅患有牙周炎(中位数 3.2 mg/L,四分位数间距 [IQR]1.8,P = 0.012)、合并粘膜炎(3.10 mg/L,IQR 2.35,P 3 mg/L,几率比例 = 7.3,95% 置信区间 1.6-33.9)的参与者 CRP 水平明显更高:种植体周围疾病与全身炎症有关,但这种关联的性质有待进一步研究。
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来源期刊
Journal of periodontology
Journal of periodontology 医学-牙科与口腔外科
CiteScore
9.10
自引率
7.00%
发文量
290
审稿时长
3-8 weeks
期刊介绍: The Journal of Periodontology publishes articles relevant to the science and practice of periodontics and related areas.
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