Blood test for early Parkinson disease diagnosis

IF 28.2 1区医学 Q1 CLINICAL NEUROLOGY

Nature Reviews Neurology Pub Date : 2024-05-14 DOI:10.1038/s41582-024-00970-y

Lisa Kiani

引用次数: 0

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用于早期诊断帕金森病的血液检测

新研究表明，基于血液的α-突触核蛋白（α-syn）种子扩增测定（SAA）可在临床诊断前10年检测出帕金森病（PD）。对12名帕金森病患者的血样进行的回顾性分析表明，所有患者在确诊前1-10年的α-syn SAA均呈阳性。所有健康对照组（13人）的SAA结果均为阴性，而30%的孤立性快速眼动睡眠行为障碍患者（20人）的SAA结果为阳性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neurology 医学-临床神经学

CiteScore

29.90

自引率

0.80%

发文量

138

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.