A numerical investigation for the development of functionally graded Ti/HA tibial implant for total ankle replacement: Influence of material gradation law and volume fraction index

IF 3.2 4区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of biomedical materials research. Part B, Applied biomaterials Pub Date : 2024-05-14 DOI:10.1002/jbm.b.35417

Jyoti, Rajesh Ghosh

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引用次数: 0

Abstract

Stress shielding is one of the major concerns for total ankle replacement implants nowadays, because it is responsible for implant-induced bone resorption. The bone resorption contributes to the aseptic loosening and failure of ankle implants in later stages. To reduce the stress shielding, improvements can be made in the implant material by decreasing the elastic mismatch between the implant and the tibia bone. This study proposes a new functionally graded material (FGM) based tibial implant for minimizing the problem of stress shielding. Three-dimensional finite element (FE) models of the intact tibia and the implanted tibiae were created to study the influence of material gradation law and volume fraction index on stress shielding and implant-bone micromotion. Different implant materials were considered that is, cobalt–chromium, titanium (Ti), and FGM with Ti at the bottom and hydroxyapatite (HA) at the top. The FE models of FGM implants were generated by using different volume fractions and the rule of mixtures. The rule of mixtures was used to calculate the FGM properties based on the local volume fraction. The volume fraction was defined by using exponential, power, and sigmoid laws. For the power and sigmoid law varying volume fraction indices (0.1, 0.2, 0.5, 1, 2, and 5) were considered. The geometry resembling STAR® ankle system tibial implant was considered for the present study. The results indicate that FGMs lower stress shielding but also marginally increase implant-bone micromotion; however, the values were within the acceptable limit for bone ingrowth. It is observed that the material gradation law and volume fraction index influence the performance of FGM tibial implants. The tibial implant composed of FGM using power law with a volume fraction index of 0.1 was the preferred option because it showed the least stress shielding.

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开发用于全踝关节置换的功能分级 Ti/HA 胫骨植入物的数值研究：材料分级法和体积分数指数的影响。

应力屏蔽是目前全踝关节置换植入物的主要问题之一，因为它会导致植入物引起的骨吸收。骨吸收是踝关节植入物后期无菌松动和失效的原因之一。为了减少应力屏蔽，可以通过减少植入物与胫骨之间的弹性不匹配来改进植入物材料。本研究提出了一种基于功能分级材料（FGM）的新型胫骨植入物，以尽量减少应力屏蔽问题。研究人员创建了完整胫骨和植入胫骨的三维有限元（FE）模型，以研究材料分级法则和体积分数指数对应力屏蔽和植入体-骨微动的影响。研究考虑了不同的植入材料，即钴铬、钛（Ti）和底部为钛顶部为羟基磷灰石（HA）的 FGM。使用不同的体积分数和混合物法则生成了 FGM 植入物的 FE 模型。混合物规则用于计算基于局部体积分数的 FGM 特性。体积分数是通过使用指数律、幂律和西格码律来定义的。对于幂定律和西格玛定律，考虑了不同的体积分数指数（0.1、0.2、0.5、1、2 和 5）。本研究考虑了类似 STAR® 踝关节系统胫骨植入物的几何形状。结果表明，FGM 降低了应力屏蔽，但也略微增加了植入物与骨之间的微动；不过，这些值都在骨生长的可接受范围内。据观察，材料分级法和体积分数指数会影响 FGM 胫骨植入物的性能。采用幂次法、体积分数指数为 0.1 的 FGM胫骨植入体是首选方案，因为它的应力屏蔽最小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of biomedical materials research. Part B, Applied biomaterials 工程技术-材料科学：生物材料

CiteScore

7.50

自引率

2.90%

发文量

199

审稿时长

12 months

期刊介绍： Journal of Biomedical Materials Research – Part B: Applied Biomaterials is a highly interdisciplinary peer-reviewed journal serving the needs of biomaterials professionals who design, develop, produce and apply biomaterials and medical devices. It has the common focus of biomaterials applied to the human body and covers all disciplines where medical devices are used. Papers are published on biomaterials related to medical device development and manufacture, degradation in the body, nano- and biomimetic- biomaterials interactions, mechanics of biomaterials, implant retrieval and analysis, tissue-biomaterial surface interactions, wound healing, infection, drug delivery, standards and regulation of devices, animal and pre-clinical studies of biomaterials and medical devices, and tissue-biopolymer-material combination products. Manuscripts are published in one of six formats: • original research reports • short research and development reports • scientific reviews • current concepts articles • special reports • editorials Journal of Biomedical Materials Research – Part B: Applied Biomaterials is an official journal of the Society for Biomaterials, Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Manuscripts from all countries are invited but must be in English. Authors are not required to be members of the affiliated Societies, but members of these societies are encouraged to submit their work to the journal for consideration.