Change in Lumbar Lordosis After Decompressive Surgery in Lumbar Spinal Stenosis Patients and Associations With Patient-Related Outcomes Two Years After Surgery: Radiologic and Clinical Results From the NORDSTEN Spinal Stenosis Trial.

IF 2.6 2区 医学 Q2 CLINICAL NEUROLOGY
Spine Pub Date : 2025-01-01 Epub Date: 2024-05-13 DOI:10.1097/BRS.0000000000005037
Josefin Åkerstedt, Johan Wänman, Hasan Banitalebi, Tor Åge Myklebust, Clemens Weber, Kjersti Storheim, Christian Hellum, Kari Indrekvam, Erland Hermansen, Helena Brisby
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Abstract

Study design: A prospective cohort study.

Objective: The aim was to investigate changes in lumbar lordosis (LL) and its association to changes in patient-reported outcome measures (PROMs) after decompressive surgery for lumbar spinal stenosis (LSS).

Summary of background: Few studies have addressed change in LL after decompression surgery for LSS in relation to outcomes.

Materials and methods: Preoperative and postoperative data from 310 patients having standing x-ray both before and two years after surgery were included. The patients were grouped based on the change in LL preoperatively to two years after surgery; group 1: <5° (n=196), group 2: ≥5 <10° (n=55), or group 3: ≥10° (n=59) of change in LL. The changes in function, disability and pain were assessed by the Oswestry disability index (ODI), numeric rating scale (NRS), and the Zurich claudication questionnaire (ZCQ). The three groups were compared regarding baseline variables using the ANOVA test for continuous variables and the χ 2 test for categorical variables. The groups were further compared with a likelihood ratio test in relation to changes in PROMs two years after surgery and outcomes were adjusted for respective baseline PROMs, age, sex, smoking, BMI, Schizas, and Pfirrmann scores.

Results: LL was significantly changed at group level two years after surgery with a mean difference of 2.2° (SD: 9.4°) ( P =0.001). The three LL change groups did not show any significant differences in patient characteristics, function, disability, and pain at baseline. The two groups with a change of more than 5° in LL two years after surgery (group 2 and 3) had significantly greater improvements in ODI ( P =0.022) and ZCQ function ( P =0.016) in the adjusted analyses, but was not significant for back and leg pain.

Conclusion: Changed LL after decompressive surgery for LSS was associated with improved ODI and physical function.

Level of Evidence. Level III.

腰椎管狭窄症患者减压手术后腰椎前凸的变化及与术后两年患者相关结果的关系。NORDSTEN椎管狭窄症试验的放射学和临床结果。
研究设计前瞻性队列研究:目的: 研究腰椎管狭窄症(LSS)减压手术后腰椎前凸(LL)的变化及其与患者报告结果指标(PROMs)变化的关系:很少有研究涉及腰椎管狭窄症减压手术后 LL 的变化与疗效的关系:方法:研究纳入了 310 名患者的术前和术后数据,这些患者在手术前和手术后 2 年都接受了站立 X 光检查。根据术前至术后 2 年 LL 的变化情况对患者进行分组;第 1 组:结果:术后 2 年 LL 有显著变化;第 2 组:结果:术后 2 年 LL 有显著变化:术后 2 年,各组 LL 均有明显变化,平均相差 2.2 度(标准差 9.4 度)(P =0.001)。三个 LL 变化组在基线时的患者特征、功能、残疾和疼痛方面均无明显差异。在调整分析中,术后2年LL变化超过5度的两组(第2组和第3组)在ODI(P =0.022)和ZCQ功能(P =0.016)方面有明显改善,但在腰腿痛方面无明显改善:结论:LSS减压手术后LL的改变与ODI和身体功能的改善有关。
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来源期刊
Spine
Spine 医学-临床神经学
CiteScore
5.90
自引率
6.70%
发文量
361
审稿时长
6.0 months
期刊介绍: Lippincott Williams & Wilkins is a leading international publisher of professional health information for physicians, nurses, specialized clinicians and students. For a complete listing of titles currently published by Lippincott Williams & Wilkins and detailed information about print, online, and other offerings, please visit the LWW Online Store. Recognized internationally as the leading journal in its field, Spine is an international, peer-reviewed, bi-weekly periodical that considers for publication original articles in the field of Spine. It is the leading subspecialty journal for the treatment of spinal disorders. Only original papers are considered for publication with the understanding that they are contributed solely to Spine. The Journal does not publish articles reporting material that has been reported at length elsewhere.
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