Recent advancements in ¹⁸F-FDG PET/CT for the diagnosis, staging, and treatment management of HIV-related lymphoma.

IF 2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

American journal of nuclear medicine and molecular imaging Pub Date : 2024-04-25 eCollection Date: 2024-01-01 DOI:10.62347/QPAS5990

Ghazaleh Jamalipour Soufi, Ali Hekmatnia, Farzaneh Hekmatnia, Andrew Parviz Zarei, Shamim Shafieyoon, Sara Azizollahi, Mohamad Ghazanfari Hashemi, Farshad Riahi

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引用次数: 0

Abstract

Infection with the Human Immunodeficiency Virus (HIV) is one of the most pressing issues facing public health on a worldwide scale. Currently, HIV-related lymphoma is the most common cause of death among people living with HIV, and warrants more attention. The unique challenges associated with HIV-related lymphoma management derive from the underlying HIV infection and its immunosuppressive effects. ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) has gained significant prominence in the past few years as a valuable diagnostic and therapeutic instrument for the treatment of HIV-related lymphoma. This review will start with an overview of the subtypes, risk factors, and therapeutic choices for individuals with HIV-related lymphoma. We will then briefly discuss the current application of ¹⁸F-FDG PET/CT in the medical management of HIV-related lymphoma patients, followed by the initial staging of the disease, the evaluation of therapeutic response, the prediction of prognostic outcomes, the decision-making process for radiotherapy guided by PET findings, and the distinguishing of various diagnoses.

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18F-FDG PET/CT 在艾滋病相关淋巴瘤的诊断、分期和治疗管理方面的最新进展。

人类免疫缺陷病毒（HIV）感染是全球公共卫生面临的最紧迫问题之一。目前，HIV 相关淋巴瘤是导致 HIV 感染者死亡的最常见原因，值得更多关注。与 HIV 相关的淋巴瘤治疗所面临的独特挑战来自于潜在的 HIV 感染及其免疫抑制效应。在过去几年中，18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（18F-FDG PET/CT）作为治疗艾滋病相关淋巴瘤的重要诊断和治疗工具，已获得了极大的重视。本综述将首先概述艾滋病相关淋巴瘤的亚型、风险因素和治疗选择。然后，我们将简要讨论 18F-FDG PET/CT 目前在艾滋病相关淋巴瘤患者医疗管理中的应用，接着讨论疾病的初步分期、治疗反应评估、预后预测、PET 发现指导下的放疗决策过程以及各种诊断的鉴别。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of nuclear medicine and molecular imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

自引率

4.00%

发文量

期刊介绍： The scope of AJNMMI encompasses all areas of molecular imaging, including but not limited to: positron emission tomography (PET), single-photon emission computed tomography (SPECT), molecular magnetic resonance imaging, magnetic resonance spectroscopy, optical bioluminescence, optical fluorescence, targeted ultrasound, photoacoustic imaging, etc. AJNMMI welcomes original and review articles on both clinical investigation and preclinical research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.