Maria Letizia Lai , Jacopo Caschili , Priscilla Baldussu , Alessandra Serra , Lucia Secci , Pietro Giorgio Calò , Clara Gerosa , Daniela Fanni
{"title":"Papillary thyroid carcinoma presented as a hypercaptant nodule: a case report","authors":"Maria Letizia Lai , Jacopo Caschili , Priscilla Baldussu , Alessandra Serra , Lucia Secci , Pietro Giorgio Calò , Clara Gerosa , Daniela Fanni","doi":"10.1016/j.endmts.2024.100179","DOIUrl":null,"url":null,"abstract":"<div><p>Hot thyroid nodules are mostly benign and rarely show a malignant nature. Here we present the case of a 45-year-old man with a hypercaptant but ultrasound suspicious nodule; he underwent fine needle aspiration (FNA) and subsequent thyroidectomy. Pathology revealed a papillary thyroid carcinoma (PTC) with focal tall cell features, positivity to BRAF V600E and focal hyperspression of p53. A multidisciplinary clinicopathological approach is crucial for the correct diagnosis.</p></div>","PeriodicalId":34427,"journal":{"name":"Endocrine and Metabolic Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666396124000232/pdfft?md5=c3dc692a88467a63cd1f725f843906ab&pid=1-s2.0-S2666396124000232-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endocrine and Metabolic Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666396124000232","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Hot thyroid nodules are mostly benign and rarely show a malignant nature. Here we present the case of a 45-year-old man with a hypercaptant but ultrasound suspicious nodule; he underwent fine needle aspiration (FNA) and subsequent thyroidectomy. Pathology revealed a papillary thyroid carcinoma (PTC) with focal tall cell features, positivity to BRAF V600E and focal hyperspression of p53. A multidisciplinary clinicopathological approach is crucial for the correct diagnosis.