Pilot study comparing a new virtual reality–based visual field test to standard perimetry in children

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-06-01 DOI:10.1016/j.jaapos.2024.103933

Yeabsira Mesfin BS , Alan Kong MD , Benjamin T. Backus PhD , Michael Deiner PhD , Yvonne Ou MD , Julius T. Oatts MD

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Abstract

Purpose

To assess the feasibility and performance of Vivid Vision Perimetry (VVP), a new virtual reality (VR)–based visual field platform.

Methods

Children 7-18 years of age with visual acuity of 20/80 or better undergoing Humphrey visual field (HVF) testing were recruited to perform VVP, a VR-based test that uses suprathreshold stimuli to test 54 field locations and calculates a fraction seen score. Pearson correlation coefficients were calculated to evaluate correlation between HVF mean sensitivity and VVP mean fraction seen scores. Participants were surveyed regarding their experience.

Results

A total of 37 eyes of 23 participants (average age, 12.9 ± 3.1 years; 48% female) were included. All participants successfully completed VVP testing. Diagnoses included glaucoma (12), glaucoma suspect (7), steroid-induced ocular hypertension (3), and craniopharyngioma (1). Sixteen participants had prior HVF experience, and none had prior VVP experience, although 7 had previously used VR. Of the 23 HVF tests performed, 9 (39%) were unreliable due to fixation losses, false positives, or false negatives. Similarly, 35% of VVP tests were unreliable (as defined by accuracy of blind spot detection). Excluding unreliable HVF tests, the correlation between HVF average mean sensitivity and VVP mean fraction seen score was 0.48 (P = 0.02; 95% CI, 0.09-0.74). When asked about preference for the VVP or HVF examination, all participants favored the VVP, and 70% were “very satisfied” with VVP.

Conclusions

In our cohort of 23 pediatric subjects, VVP proved to be a clinically feasible VR-based visual field testing, which was uniformly preferred over HVF.

查看原文本刊更多论文

将基于虚拟现实的新型儿童视野测试与标准视力测试进行比较的试点研究。

目的：评估基于虚拟现实（VR）的全新视野平台Vivid Vision Perimetry（VVP）的可行性和性能：方法：招募视力在 20/80 或更佳的 7-18 岁儿童进行汉弗莱视野（HVF）测试，并进行 VVP 测试。VVP 是一种基于虚拟现实的测试，使用阈上刺激测试 54 个视野位置，并计算出所见分数。通过计算皮尔逊相关系数来评估 HVF 平均灵敏度与 VVP 平均可见分数之间的相关性。对参与者进行了经验调查：共纳入 23 名参与者的 37 只眼睛（平均年龄为 12.9 ± 3.1 岁；48% 为女性）。所有参与者都成功完成了 VVP 测试。诊断包括青光眼（12 例）、疑似青光眼（7 例）、类固醇引起的眼压过高（3 例）和颅咽管瘤（1 例）。16 名参与者之前有过高频荧光检测经验，没有人有过 VVP 经验，但有 7 人曾使用过 VR。在进行的 23 次 HVF 测试中，有 9 次（39%）由于固定损失、假阳性或假阴性而不可靠。同样，35% 的 VVP 测试也不可靠（以准确检测盲点为标准）。排除不可靠的 HVF 测试，HVF 平均灵敏度与 VVP 平均可见分数之间的相关性为 0.48（P = 0.02；95% CI，0.09-0.74）。当被问及对 VVP 或 HVF 检查的偏好时，所有参与者都倾向于 VVP，70% 的人对 VVP 表示 "非常满意"：在我们的 23 名儿科受试者中，VVP 被证明是一种临床上可行的基于 VR 的视野测试，与 HVF 相比，所有受试者都更倾向于 VVP。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.