Low-level laser therapy: an efficient supplement to treatments of vulvar Lichen sclerosus to improve quality of life.

IF 0.9 4区医学 Q4 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-05-10 DOI:10.1080/01443615.2024.2349965

Pia Kirstine Berthelsen, Sidsel Eb Ipsen, Mohammed R Khalil

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引用次数: 0

Abstract

Background: Lichen sclerosus (LS) is a chronic, inflammatory disease of the genital and extra genital skin, causing pruritus, soreness, pain and dyspareunia. The aim of this study was to investigate whether Low Level Laser Therapy (LLLT) can improve the quality of life in women with Lichen sclerosus (LS) and insufficient topical treatment.

Methods: In a descriptive prospective observational study conducted between 02.01.2016 and 08.01.2018, we included 100 women with LS with insufficient topical treatment because of poor response of symptoms. All participants received ten LLLT treatments (808 nm and 500 mW) over a period of 8 weeks. The first four treatments were planned as two treatments per week. The remaining six treatments were planned as once a week. A Danish health-related quality of life tool (HRQoL test) monitored the effect.

Results: A total of 94 patients completed the study, median age of 62 [InterQuartile Range 53-69]. There was a statistically significant improvement in seven of the eight domains of the HRQoL test after ten LLLT. We found the results of DoloTest to be statistically significant in all of the groups except for smoking (p < 0.094).

Conclusions: LLLT treatment can improve the quality of life in women with LS.

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低强度激光疗法：改善外阴硬皮病生活质量的有效辅助疗法。

背景：硬皮病（LS）是生殖器和生殖器外皮肤的一种慢性炎症性疾病，可引起瘙痒、酸痛、疼痛和性生活障碍。本研究旨在探讨低水平激光疗法（LLLT）能否改善患有硬皮病（LS）且局部治疗不足的女性的生活质量：在2016年1月2日至2018年1月8日期间进行的一项描述性前瞻性观察研究中，我们纳入了100名因症状反应不佳而局部治疗不足的LS女性患者。所有参与者在 8 周内接受了 10 次 LLLT 治疗（808 纳米和 500 毫瓦）。前四次治疗计划为每周两次。其余六次治疗计划为每周一次。丹麦健康相关生活质量工具（HRQoL 测试）对疗效进行监测：共有 94 名患者完成了研究，中位年龄为 62 岁[四分位间范围为 53-69 岁]。经过十次 LLLT 治疗后，在 HRQoL 测试的八个领域中，有七个领域的改善具有统计学意义。我们发现，除吸烟外，DoloTest 的结果在所有组别中均有统计学意义（p 结论：LLLT 治疗可改善患者的生活质量：LLLT 治疗可以改善 LS 妇女的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obstetrics and Gynaecology 医学-妇产科学

CiteScore

2.40

自引率

7.70%

发文量

398

审稿时长

6 months

期刊介绍： Journal of Obstetrics and Gynaecology represents an established forum for the entire field of obstetrics and gynaecology, publishing a broad range of original, peer-reviewed papers, from scientific and clinical research to reviews relevant to practice. It also includes occasional supplements on clinical symposia. The journal is read widely by trainees in our specialty and we acknowledge a major role in education in Obstetrics and Gynaecology. Past and present editors have recognized the difficulties that junior doctors encounter in achieving their first publications and spend time advising authors during their initial attempts at submission. The journal continues to attract a world-wide readership thanks to the emphasis on practical applicability and its excellent record of drawing on an international base of authors.