Second to fourth digit ratio (2D:4D) as the 'anatomical marker' and reproductive 'hormonal fingerprint' in the occurrence dental plaque accumulation.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-10 eCollection Date: 2024-06-01 DOI:10.1515/hmbci-2023-0063

Sulagna Dutta, Chin Win Nie, Amrita Sarna, Padmini Hari, Pallav Sengupta

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引用次数: 0

Abstract

Objectives: Digit ratio (2D:4D), as endocrine fingerprint, can indicate prenatal androgen exposure. It serves as an anatomical marker for various systemic diseases and a few studies relating it to oral health. The present study aims to evaluate the association between digit ratio and susceptibility to dental plaque formation.

Methods: The study was conducted on young adults aged between 18 and 25 years. Digit ratio and reproductive hormones were measured; dental plaque score and gingival index (GI) were recorded. Data were analysed using the MedCalc. v.20.

Results: Male and female participants were categorized into two groups based on their digit ratios being either above or below the calculated average (0.99 for females, 0.98 for males). Those with a digit ratio below the average had a significantly higher mean dental plaque score (p < 0.0001) than those with ratios at or above the average. However, there was no significant difference in the GI between the two groups. Reproductive hormone profiles varied significantly between the higher and lower digit ratio groups for both sexes.

Conclusions: Digit ratio may find potential to be used as an anatomical marker to identify the susceptibility to dental plaque build-up.

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第二位数字与第四位数字之比（2D:4D）是牙菌斑堆积的 "解剖标记 "和生殖 "激素指纹"。

目的：数字比率（2D:4D）作为内分泌指纹，可显示产前雄激素暴露情况。它是各种全身性疾病的解剖标记，也有少数研究将其与口腔健康联系起来。本研究旨在评估数字比率与牙菌斑形成易感性之间的关联：研究对象为 18 至 25 岁的年轻人。方法：研究对象为 18 至 25 岁的年轻人，测量了数字比率和生殖激素；记录了牙菌斑评分和牙龈指数（GI）。使用 MedCalc：男性和女性参与者根据其数字比率高于或低于计算得出的平均值（女性为 0.99，男性为 0.98）被分为两组。数字比率低于平均值者的牙菌斑平均得分（p < 0.0001）明显高于数字比率达到或高于平均值者。不过，两组人的消化道指数没有明显差异。男女两性的生殖激素谱在数字比率较高和较低的组别之间存在显著差异：结论：数字比率可作为一种解剖标记，用于识别牙菌斑堆积的易感性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.