O. M. Razumnikova, I. V. Tarasova, Yu. A. Mezentsev, P. S. Pavlov, O. A. Trubnikova
{"title":"Identification of the Profile of Cognitive Deficit in Cardiac Surgery Patients Using the Optimal Clustering Method","authors":"O. M. Razumnikova, I. V. Tarasova, Yu. A. Mezentsev, P. S. Pavlov, O. A. Trubnikova","doi":"10.1134/s0022093024020169","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>An original clustering method based on discrete optimization\nof multidimensional objects according to many heterogeneous parameters:\nage, severity of carotid artery stenosis (CA), personal and cognitive characteristics\nwas used to identify pre- and postoperative specificity of the profile\nof cognitive functions. The study involved 163 cardiac surgery patients.\nDetermination of CA stenosis was carried out in the preoperative\nperiod using color duplex scanning and further classification of\nthe lesion. Psychometric assessment of personal and situational\nanxiety, as well as psychomotor and executive functions, attention,\nshort-term memory was performed 3–5 days before and 7–10 days after\ncoronary artery bypass surgery (CABG). As a result of clustering\narrays of 17 normalized indicators and subsequent analysis of three\ngroups formed in this way, different dynamics of restoration of\nthe profile of cognitive functions after CABG were discovered. One\nof the groups was designated as a group of cognitive reserves according\nto its best indicators of information selection and memory both\nin the preoperative and postoperative periods. Another selected\ngroup was characterized by a postoperative increase in the speed of\ninformation selection, but low memory scores. The third selected\ngroup demonstrated close relationships between indicators of attention,\nmemory and the efficiency of a complex visual-motor reaction with\nage and the degree of stenosis of the CA, regardless of the pre-\nor postoperative testing period, which may indicate persistent disorganization\nof cognitive functions in such patients, requiring special attention\nwhen choosing neuro- and cardiac rehabilitation programs for them.\nThe developed clustering method makes it possible to group patients\naccording to a variety of heterogeneous parameters to identify the\ndynamics of their changes during the course of treatment.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"116 1","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Evolutionary Biochemistry and Physiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1134/s0022093024020169","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
An original clustering method based on discrete optimization
of multidimensional objects according to many heterogeneous parameters:
age, severity of carotid artery stenosis (CA), personal and cognitive characteristics
was used to identify pre- and postoperative specificity of the profile
of cognitive functions. The study involved 163 cardiac surgery patients.
Determination of CA stenosis was carried out in the preoperative
period using color duplex scanning and further classification of
the lesion. Psychometric assessment of personal and situational
anxiety, as well as psychomotor and executive functions, attention,
short-term memory was performed 3–5 days before and 7–10 days after
coronary artery bypass surgery (CABG). As a result of clustering
arrays of 17 normalized indicators and subsequent analysis of three
groups formed in this way, different dynamics of restoration of
the profile of cognitive functions after CABG were discovered. One
of the groups was designated as a group of cognitive reserves according
to its best indicators of information selection and memory both
in the preoperative and postoperative periods. Another selected
group was characterized by a postoperative increase in the speed of
information selection, but low memory scores. The third selected
group demonstrated close relationships between indicators of attention,
memory and the efficiency of a complex visual-motor reaction with
age and the degree of stenosis of the CA, regardless of the pre-
or postoperative testing period, which may indicate persistent disorganization
of cognitive functions in such patients, requiring special attention
when choosing neuro- and cardiac rehabilitation programs for them.
The developed clustering method makes it possible to group patients
according to a variety of heterogeneous parameters to identify the
dynamics of their changes during the course of treatment.
期刊介绍：
Journal of Evolutionary Biochemistry and Physiology publishes original experimental and theoretical and review articles related to evolution of the main forms of metabolism in connection with life origin; comparative and ontogenetic physiology and biochemistry, biochemical evolution of animal world; as well as evolution of functions; morphology, pharmacology, pathophysiology and ecological physiology. The journal welcomes manuscripts from all countries in the English or Russian language.
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