Evaluation of the Influence of Chromium and Zinc Ions on the Collagenolysis Process in Solutions by the Method of Dynamic Light Scattering

Abstract

Using the method of dynamic light scattering, it was found that the rate of collagen cleavage under the influence of bacterial collagenase decreases by almost 4 times when protein molecules are doped with Cr³⁺ ions, and when the enzyme activator of Zn²⁺ ions is added, it increases by 1.3 times. Based on the experimental data, the reaction rate constants k₁ were calculated. It was found that when collagen molecules are tanned with a chromium salt, it becomes more resistant to degradation in solutions containing zinc ions than in solutions with the addition of calcium ions, as we described in earlier works.