Validation and Application of an LC–MS/MS Method for the Determination of Antioxidants Originating from Commercial Polyethylene Packages and their Migration into Food Simulants

IF 2.6 3区农林科学 Q2 FOOD SCIENCE & TECHNOLOGY

Food Analytical Methods Pub Date : 2024-05-07 DOI:10.1007/s12161-024-02631-8

Toma Petrulionienė, Tomas Murauskas, Evaldas Naujalis

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Abstract

Plastics are remarkable due to their chemical and physical properties and are used in many fields, especially food packaging. To produce the packages, during the manufacturing processes, an array of additives such as plasticisers, stabilisers, antioxidants, lubricants, and pigments is required. Unfortunately, most additives can migrate and contaminate the food they are intended to hold and preserve. Identifying potential migrants is likely the only way to gain knowledge, improve the manufacturing processes, and assess potential health risks related to the migration of additives and their degradation products to food media. Therefore, in this study, commercial polyethylene packages were investigated using validated liquid chromatography with tandem mass spectrometry (LC–MS/MS) method to reliably quantify the content of the antioxidants Irganox 1010 and Irgafos 168-ox and their migration levels to food simulants representing foods having hydrophilic and lipophilic properties. The results revealed the highly varying amount of antioxidants in different types of polyethylene food contact materials.

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验证和应用 LC-MS/MS 方法测定商用聚乙烯包装中的抗氧化剂及其向食品模拟物中的迁移量

塑料因其化学和物理特性而引人注目，被广泛应用于许多领域，尤其是食品包装。为了生产这些包装，在制造过程中需要使用一系列添加剂，如增塑剂、稳定剂、抗氧化剂、润滑剂和颜料。不幸的是，大多数添加剂都会迁移并污染它们用来盛放和保存的食品。要想了解添加剂及其降解产物迁移到食品介质中的相关知识、改进生产工艺并评估潜在的健康风险，识别潜在的迁移者可能是唯一的途径。因此，本研究采用经过验证的液相色谱-串联质谱（LC-MS/MS）方法对商用聚乙烯包装进行了调查，以可靠地量化抗氧化剂 Irganox 1010 和 Irgafos 168-ox 的含量及其向具有亲水性和亲油性的食品模拟物中的迁移水平。结果显示，不同类型的聚乙烯食品接触材料中抗氧化剂的含量差异很大。

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来源期刊

Food Analytical Methods 农林科学-食品科技

CiteScore

6.00

自引率

3.40%

发文量

244

审稿时长

3.1 months

期刊介绍： Food Analytical Methods publishes original articles, review articles, and notes on novel and/or state-of-the-art analytical methods or issues to be solved, as well as significant improvements or interesting applications to existing methods. These include analytical technology and methodology for food microbial contaminants, food chemistry and toxicology, food quality, food authenticity and food traceability. The journal covers fundamental and specific aspects of the development, optimization, and practical implementation in routine laboratories, and validation of food analytical methods for the monitoring of food safety and quality.