Effects of combined resistance training and Tai Chi on oxidative stress, blood glucose and lipid metabolism and quality of life in elderly patients with type 2 diabetes mellitus.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-01 Epub Date: 2024-05-07 DOI:10.1080/15438627.2024.2349521

Shuwan Chang, Heng Liu

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引用次数: 0

Abstract

This study examined the effects of resistance training (RT), Tai Chi (TC) and combination intervention (RT & TC) on the oxidative stress, blood glucose and lipid metabolism and quality of life of elderly patients with type 2 diabetes mellitus (T2DM). Ninety-four elderly patients with T2DM were randomly divided into an RT group (RTG, n = 23), TC group (TCG, n = 24), combination intervention group (CIG, n = 24) and control group (CG, n = 23). All participants were given nutrition and medication. On this basis, RTG, TCG and CIG were administered for 24 weeks (3 times/week, 40 minutes/time). Observation indicators were malondialdehyde (MDA), superoxide dismutase (SOD), 8-hydroxy-2 deoxyguanosine (8-OHdG), fasting plasma glucose (FPG), postprandial plasma glucose (PPG), haemoglobin A1c (HbA1c) and diabetes specific quality of life (DSQL). RT, TC and joint intervention can reduce the oxidative stress damage on elderly patients with T2DM to different degrees, control the levels of blood sugar and blood lipid and improve the quality of life. Compared with single intervention, combination intervention can further reduce the level of oxidative stress but has no additional benefits on blood glucose and lipid control and quality of life.

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联合阻力训练和太极拳对老年 2 型糖尿病患者氧化应激、血糖和血脂代谢以及生活质量的影响。

本研究探讨了阻力训练（RT）、太极拳（TC）和联合干预（RT & TC）对老年 2 型糖尿病（T2DM）患者氧化应激、血糖和血脂代谢以及生活质量的影响。94 名老年 T2DM 患者被随机分为 RT 组（RTG，n = 23）、TC 组（TCG，n = 24）、联合干预组（CIG，n = 24）和对照组（CG，n = 23）。所有参与者都获得了营养和药物治疗。在此基础上，进行为期 24 周的 RTG、TCG 和 CIG 治疗（每周 3 次，每次 40 分钟）。观察指标包括丙二醛（MDA）、超氧化物歧化酶（SOD）、8-羟基-2-脱氧鸟苷（8-OHdG）、空腹血浆葡萄糖（FPG）、餐后血浆葡萄糖（PPG）、血红蛋白 A1c（HbA1c）和糖尿病特定生活质量（DSQL）。RT、TC和联合干预能不同程度地减轻T2DM老年患者的氧化应激损伤，控制血糖和血脂水平，改善生活质量。与单一干预相比，联合干预可进一步降低氧化应激水平，但对血糖、血脂控制和生活质量无额外益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.