Evaluation of the Impact of Adaptive Progressive Supervised Resistance Training on Strength and Quality of Life in Patients with Breast Cancer during Chemotherapy: The VALESCO Study.

IF 2 4区 医学 Q3 ONCOLOGY
Oncology Research and Treatment Pub Date : 2024-01-01 Epub Date: 2024-05-07 DOI:10.1159/000539087
Lars Gerland, Nadia Harbeck, Susanne Frisse, Wilhelm Bloch, Wolfram Malter, Ronald Kates, Freerk Theeagnus Baumann
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引用次数: 0

Abstract

Introduction: Breast cancer patients (BCP) experience considerable side effects during and after treatment. Several studies have shown positive effects of exercise on therapy-related side-effects such as loss of muscle strength, loss of bone mineral density, lymphedema, and several elements of quality of life (QoL). Resistance exercise has proven effective and beneficial for BCP; however, optimal individual training parameters remain to be determined.

Methods: The aim of our study was to implement an adaptive, progressive, supervised resistance protocol for BCPs during chemotherapy, improving muscle strength, physical condition, and overall QoL while reducing therapy-induced side-effects. Forty patients receiving adjuvant chemotherapy were included 6-12 weeks post-OP. Twenty patients underwent high intensity resistance-training twice a week for 12 weeks, and the control group received usual care.

Results: Strength parameters improved significantly in the intervention group and in different scales of QoL. We documented a cyclic performance level dependent on the number of days after treatment.

Conclusion: Adaptive resistance training with simple training control mechanisms proved to be effective regarding optimal intensity in each training session and needs to be implemented in further studies in order to guarantee adequate loads in accordance to the training protocols.

评估适应性渐进监督阻力训练对化疗期间乳腺癌患者力量和生活质量的影响:VALESCO研究
导言:乳腺癌患者(BCP)在治疗期间和治疗后都会经历相当大的副作用。多项研究表明,运动对治疗相关的副作用有积极影响,如肌肉力量下降、骨矿物质密度下降、淋巴水肿以及生活质量(QoL)的若干因素。阻力运动已被证明对 BCP 有效且有益,但最佳的个人训练参数仍有待确定:我们的研究旨在为化疗期间的乳腺癌患者实施一套适应性强、循序渐进、有监督的抗阻力训练方案,以改善患者的肌肉力量、身体状况和整体生活质量,同时减少治疗引起的副作用。40 名接受辅助化疗的患者在术后六到十二周内接受了治疗。20 名患者接受了每周两次、为期 12 周的高强度阻力训练,对照组则接受常规护理:结果:干预组的力量参数和不同的 QoL 量表均有明显改善。我们记录了一个周期性的表现水平,强调了适应性训练和训练控制在进一步试验中的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
84
期刊介绍: With the first issue in 2014, the journal ''Onkologie'' has changed its title to ''Oncology Research and Treatment''. By this change, publisher and editor set the scene for the further development of this interdisciplinary journal. The English title makes it clear that the articles are published in English – a logical step for the journal, which is listed in all relevant international databases. For excellent manuscripts, a ''Fast Track'' was introduced: The review is carried out within 2 weeks; after acceptance the papers are published online within 14 days and immediately released as ''Editor’s Choice'' to provide the authors with maximum visibility of their results. Interesting case reports are published in the section ''Novel Insights from Clinical Practice'' which clearly highlights the scientific advances which the report presents.
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