Anti-rubella seroprevalence assessment in an adult sample population in Italy.

IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Angela Bechini, Beatrice Zanella, Benedetta Bonito, Marta Betti, Enrica Stancanelli, Marco Del Riccio, Cristina Salvati, Paolo Bonanni, Jacopo Bianchi, Ilaria Biondi, Martina Chellini, Maddalena Innocenti, Federico Manzi, Diana Paolini, Gino Sartor, Lorenzo Baggiani, Simona Baretti, Monica Della Fonte, Giorgio Garofalo, Giovanna Mereu, Maria Grazia Santini, Sara Boccalini
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引用次数: 0

Abstract

Introduction: Despite global immunization efforts, rubella remains a public health concern, particularly in high- and middle-income countries. This study focused on rubella seroprevalence in the province of Florence, Italy, aiming to identify susceptibility clusters, especially among women in their childbearing age.

Methods: A cross-sectional study was conducted between April 2018 and December 2019, enrolling 430 adult subjects (age over 18 years). Serum samples were collected, and anti-rubella antibodies were quantified using the ELISA test. Data were analyzed descriptively and compared by sex, nationality, and age groups using statistical tests.

Results: The overall rubella seroprevalence was high (92.3%), with no significant differences between genders or nationalities. Among childbearing-age females (18-49 years), the highest seroprevalence was observed in the 30-39 age group (94.1%). However, susceptibility clusters exceeding the 5% threshold set by WHO were identified, especially in females aged 40-49 years (7.0%).

Conclusions: Despite high overall seroprevalence, the study identified pockets of susceptibility, even in childbearing age women. Continuous monitoring, targeted immunization strategies, and public health interventions are recommended to maintain rubella elimination, emphasizing the importance of sustained vaccination efforts to protect vulnerable populations.

意大利成人样本人群抗风疹血清流行率评估。
导言:尽管全球都在努力接种风疹疫苗,但风疹仍然是一个公共卫生问题,尤其是在中高收入国家。本研究重点关注意大利佛罗伦萨省的风疹血清流行情况,旨在确定易感人群,尤其是育龄妇女:2018年4月至2019年12月期间进行了一项横断面研究,共招募了430名成年受试者(18岁以上)。收集血清样本,并使用 ELISA 试验对抗风疹抗体进行量化。对数据进行了描述性分析,并通过统计检验对不同性别、国籍和年龄组的数据进行了比较:结果:风疹血清阳性率总体较高(92.3%),性别和国籍之间无明显差异。在育龄女性(18-49 岁)中,30-39 岁年龄组的血清阳性率最高(94.1%)。然而,在40-49岁女性(7.0%)中也发现了超过世界卫生组织规定的5%阈值的易感人群:结论:尽管总体血清流行率较高,但该研究发现了易感人群,甚至在育龄妇女中也存在易感人群。建议通过持续监测、有针对性的免疫战略和公共卫生干预措施来保持风疹的消除,同时强调持续接种疫苗以保护易感人群的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annali di igiene : medicina preventiva e di comunita
Annali di igiene : medicina preventiva e di comunita HEALTH CARE SCIENCES & SERVICES-
CiteScore
3.40
自引率
0.00%
发文量
69
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