Accuracy of endobronchial ultrasound (EBUS) in the staging of lung cancer - A comparison of staging EBUS with postoperative pathological nodal staging.

IF 1.3 Q4 RESPIRATORY SYSTEM

Lung India Pub Date : 2024-03-01 Epub Date: 2024-02-27 DOI:10.4103/lungindia.lungindia_449_23

Eshita Shah, N Sankara Raman, Manish K Aggarwal, Amit Jain, Arushi Chokhani, Avinash Murugan, Rajiv Goyal, Laengmawia Darlong, Ullas Batra

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Abstract

Background: Endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TBNA) has replaced mediastinoscopy as the preferred investigation for evaluating mediastinum in staging lung cancer. There is little evidence of mediastinal staging by EBUS-TBNA from India.

Objectives: To study endobronchial ultrasound's diagnostic accuracy in staging lung cancer.

Methodology: We retrospectively analysed patients operated on for lung cancer where EBUS was performed preoperatively for mediastinal staging. We compared the histological findings obtained from different mediastinal lymph nodes (LNs) by EBUS-TBNA with the pathology of the same LNs obtained after surgical dissection as the reference standard.

Results: Seventy-six patients underwent curative surgery for lung cancer. The diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive value of EBUS-TBNA in predicting mediastinal metastasis were 93.9%, 40%, 99%, 80% and 94.6%, respectively. Of the 115 LNs sampled, EBUS-TBNA was false negative in six nodes, resulting in an up-staging of six patients.

Conclusions: EBUS-TBNA has a high diagnostic accuracy for lung cancer staging.

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支气管内超声（EBUS）在肺癌分期中的准确性--EBUS分期与术后病理结节分期的比较。

背景：支气管内超声引导下经支气管细针穿刺术（EBUS-TBNA）已取代纵隔镜检查，成为评估肺癌纵隔分期的首选检查方法。在印度，通过 EBUS-TBNA 进行纵隔分期的证据很少：研究支气管内超声对肺癌分期的诊断准确性：我们回顾性地分析了接受肺癌手术的患者，这些患者在术前进行了EBUS纵隔分期。我们将通过 EBUS-TBNA 获得的不同纵隔淋巴结（LN）的组织学结果与手术切除后获得的相同 LN 的病理学结果作为参考标准进行了比较：76名肺癌患者接受了根治性手术。EBUS-TBNA 预测纵隔转移的诊断准确率、敏感性、特异性、阳性预测值和阴性预测值分别为 93.9%、40%、99%、80% 和 94.6%。在取样的115个纵隔中，EBUS-TBNA对6个结节的预测为假阴性，导致6名患者向上分期：结论：EBUS-TBNA 对肺癌分期的诊断准确率很高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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