Atrial Septal Abnormalities and Cryptogenic Stroke: A Cross-Sectional Study.

Marzieh Aliramezany, Mansoor Moazenzadeh, Amin Sayyadi, Khadijeh Mohammadi, Hamidreza Barzegar, Maryam Aliramezany
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Abstract

Background: Cryptogenic stroke, whose underlying pathology is unknown, accounts for 30-40% of all ischemic strokes. Studies have mentioned the association between atrial septal abnormalities and cryptogenic stroke, but there are still disparities in the results among different studies.

Objective: We aimed to clarify the prevalence of atrial septal abnormalities in patients with cryptogenic stroke.

Methods: We conducted a cross-sectional study on 91 patients with cryptogenic stroke/transient ischemic attack from March 2021 to March 2022. We evaluated the demographic data of the patients and also the existence of neurologic attacks. Furthermore, echocardiography was performed to determine the type of atrial septal abnormality.

Results: Out of 91 patients with cryptogenic stroke/transient ischemic attack, 16 patients (17.5%) had patent foramen ovale, 1 man (1.1%) had atrial septal aneurysm, and 1 woman (1.1%) had an atrial septal defect. Patients with patent foramen ovale were significantly younger than those without. The size of patent foramen ovale in patients with cryptogenic stroke was larger than those with transient ischemic attack, but this difference was not significant. Also, the size of the patent foramen ovale (length and width) was not significantly related to any of the demographic variables (p-value = 0.544, 0.604).

Conclusion: Based on our results, the prevalence of atrial septal abnormalities was relatively high. Considering these issues and the importance of preventing neurological accidents in patients, especially young people, it is recommended to always consider atrial septal disorders and, if diagnosed, to carry out the necessary treatment in this field.

心房间隔异常与隐源性中风:一项横断面研究
背景:隐源性卒中的病因不明,占所有缺血性卒中的 30%-40%。有研究提到了房间隔异常与隐源性中风之间的关联,但不同研究的结果仍存在差异:目的:我们旨在明确隐源性脑卒中患者中房间隔异常的发病率:我们在 2021 年 3 月至 2022 年 3 月期间对 91 例隐源性卒中/短暂性脑缺血发作患者进行了横断面研究。我们评估了患者的人口统计学数据以及是否存在神经系统发作。此外,我们还进行了超声心动图检查,以确定房间隔异常的类型:在 91 名隐源性中风/短暂性脑缺血发作患者中,16 名患者(17.5%)患有卵圆孔未闭,1 名男性(1.1%)患有房间隔动脉瘤,1 名女性(1.1%)患有房间隔缺损。卵圆孔未闭患者的年龄明显小于无卵圆孔未闭患者。隐源性卒中患者的卵圆孔孔径大于短暂性脑缺血发作患者,但差异不显著。此外,卵圆孔的大小(长度和宽度)与任何人口统计学变量均无明显关系(P 值 = 0.544,0.604):根据我们的研究结果,房间隔异常的发病率相对较高。考虑到这些问题以及预防患者(尤其是年轻人)发生神经系统意外的重要性,建议经常考虑房间隔疾病,如果确诊,应在该领域进行必要的治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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