Crowdsourced Partner Services Among Men Who Have Sex With Men Living With HIV: A Pilot Randomized Controlled Trial in China.

IF 2.4 4区 医学 Q3 INFECTIOUS DISEASES
Sexually transmitted diseases Pub Date : 2024-10-01 Epub Date: 2024-05-01 DOI:10.1097/OLQ.0000000000001989
Xumeng Yan, Joseph D Tucker, William C Miller, Huifang Xu, Yi Zhou, Yuzhou Gu, Meichun Chen, Meiqing Liang, Jie Lu, Lishan Zhan, Weiming Tang
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引用次数: 0

Abstract

Background: This study aimed to assess the acceptability, feasibility, and preliminary effectiveness of a crowdsourced HIV partner services (PS) intervention among men who have sex with men living with HIV (MLWH) in China.

Methods: A pilot 2-arm randomized controlled trial was conducted in 3 HIV testing clinics in China. The control arm received conventional HIV PS, whereas the intervention arm received a crowdsourced intervention, including HIV self-testing kits for secondary distribution (HIVST-SD), digital education materials, and assisted PS. The intervention was developed through 2-phase crowdsourcing events including an open call and a Designathon. The primary outcomes were measured by the 3-month follow-up rate (i.e., the proportion of participants who completed the follow-up survey to report HIV PS outcomes 3 months after enrollment) and the frequency of using intervention components (feasibility), index evaluation of intervention components (acceptability), and the proportion of partners getting HIV testing (preliminary effectiveness).

Results: The study enrolled 121 newly diagnosed MLWH between July 2021 and May 2022. The 3-month follow-up rates were 93% (75 of 81) and 83% (33 of 40) in the intervention and control arms, respectively. Crowdsourced intervention components demonstrated feasibility, with all indexes using digital educational materials, 23 successfully using HIVST-SD, and 6 employing provider-referral to notify 9 sexual partners. Acceptability was high, with HIVST-SD and digital educational materials rated 4.4 and 4.1 out of 5. The proportion of partners receiving HIV testing was 11% higher in the intervention arm than in the control arm (marginal significance with 95% confidence interval, -2% to 24%; 38% vs. 27%).

Conclusions: The crowdsourced HIV PS intervention was acceptable and feasible, suggesting the potential to facilitate partner HIV testing among Chinese MLWH. Further implementation research is recommended to expand HIV PS among key populations in low- and middle-income countries.

Clinical trial registration id: NCT04971967 (Protocol ID: 19-0496).

为感染艾滋病病毒的男男性行为者提供众包伴侣服务:中国试点随机对照试验。
背景:本研究旨在评估众包艾滋病伴侣服务(PS)干预措施在中国男男性行为者中的可接受性、可行性和初步有效性:本研究旨在评估众包艾滋病伴侣服务(PS)干预措施在中国男男性行为者(MLWH)中的可接受性、可行性和初步有效性:方法:在中国的三家 HIV 检测诊所开展了一项双臂随机对照试验(RCT)。对照组接受传统的 HIV PS,干预组接受众包干预,包括用于二次分发的 HIV 自我检测包(HIVST-SD)、数字教育材料和辅助 PS。干预措施是通过两个阶段的众包活动开发的,包括公开征集和设计马拉松。主要结果由 3 个月的随访率(即完成随访调查以报告入组 3 个月后 HIV PS 结果的参与者比例)、干预组件的使用频率(可行性)、干预组件的指数评估(可接受性)和获得 HIV 检测的伴侣比例(初步有效性)来衡量:该研究在 2021 年 7 月至 2022 年 5 月期间招募了 121 名新确诊的产妇。干预组和对照组的 3 个月随访率分别为 93%(75/81)和 83%(33/40)。众包干预内容证明了其可行性,所有指数都使用了数字教育材料,23 个指数成功使用了 HIVST-SD,6 个指数通过提供者转介通知了 9 个性伴侣。可接受性很高,HIVST-SD 和数字教育材料的评分分别为 4-4 分和 4.1 分(满分为 5 分)。干预组接受 HIV 检测的性伴侣比例比对照组高 11%(边缘显著性,95% CI = [-2%, 24%],38% 对 27%):结论:众包 HIV PS 干预是可接受和可行的,这表明它有可能促进中国少数民族妇女和艾滋病患者伴侣的 HIV 检测。建议进一步开展实施研究,以便在中低收入国家的重点人群中推广 HIV PS:临床试验注册编号:NCT04971967(方案编号:19-0496)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Sexually transmitted diseases
Sexually transmitted diseases 医学-传染病学
CiteScore
4.00
自引率
16.10%
发文量
289
审稿时长
3-8 weeks
期刊介绍: ​Sexually Transmitted Diseases, the official journal of the American Sexually Transmitted Diseases Association​, publishes peer-reviewed, original articles on clinical, laboratory, immunologic, epidemiologic, behavioral, public health, and historical topics pertaining to sexually transmitted diseases and related fields. Reports from the CDC and NIH provide up-to-the-minute information. A highly respected editorial board is composed of prominent scientists who are leaders in this rapidly changing field. Included in each issue are studies and developments from around the world.
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