Bruchs Membrane Opening Area Measurement in Healthy Nepalese Eyes.

Q3 Medicine

Journal of Nepal Health Research Council Pub Date : 2024-03-31 DOI:10.33314/jnhrc.v21i4.4839

Ranju Kharel Sitaula, Ganga Sagar Shah

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引用次数: 0

Abstract

Background: Bruch's membrane opening area is the circular area around the disc of Bruch's membrane, which is devoid of Bruch's membrane and can be assessed by capturing the retinal imaging system by Spectral-domain optical coherence tomography. BMOA can be a new landmark in analyzing the glaucomatous optic nerve head, myopic optic disc, optic neuropathy and uveitic disc edema. This is the first study from South Asia to evaluate the normal Bruch's membrane opening area among Nepalese eyes.

Methods: This hospital-based, cross-sectional, quantitative, observational study cross-sectional study was conducted in a tertiary eye care hospital in Nepal. Healthy immunocompetent Nepalese participants of both genders and different age groups were enrolled. The mean average Bruch's membrane opening area of each eyes, the difference in Bruch's membrane opening area between the two eyes and the gender of varying age groups were analyzed.

Results: Around 162 eyes (81 participants) were analyzed. The mean age was 56.69±17.5years. The mean average Bruch's membrane opening area of the right and left eye was 2.53±0.58 mm2 and 2.50 ±0.58 mm2. There was no significant difference in the Bruch's membrane opening area in either eye in both genders of any age group.

Conclusion: The Bruch's membrane opening area does not differ significantly according to the laterality, gender and age group in Nepalese eyes.

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尼泊尔健康眼睛的布氏膜开口面积测量。

背景：布氏膜开口区是布氏膜盘周围没有布氏膜的圆形区域，可通过光谱域光学相干断层扫描捕捉视网膜成像系统进行评估。BMOA 可作为分析青光眼视神经头、近视视盘、视神经病变和葡萄膜炎视盘水肿的新标志。这是南亚地区第一项评估尼泊尔人正常布鲁氏膜开口面积的研究：这项基于医院的横断面定量观察研究在尼泊尔一家三级眼科医院进行。研究对象为免疫功能正常的尼泊尔人，包括男女和不同年龄组。研究分析了每只眼睛的平均布氏膜张开面积、两只眼睛布氏膜张开面积的差异以及不同年龄组别的性别：结果：共分析了约 162 只眼睛（81 名参与者）。平均年龄为（56.69±17.5）岁。左右眼平均布氏膜开口面积分别为 2.53±0.58 mm2 和 2.50 ±0.58 mm2。结论：结论：尼泊尔人的布氏膜开口面积在侧位、性别和年龄组中没有明显差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Nepal Health Research Council Medicine-Medicine (all)

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

15 weeks

期刊介绍： The journal publishes articles related to researches done in the field of biomedical sciences related to all the discipline of the medical sciences, medical education, public health, health care management, including ethical and social issues pertaining to health. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews and meta-analysis. Editorial, Guest Editorial, Viewpoint and letter to the editor are solicited by the editorial board. Frequently Asked Questions (FAQ) regarding manuscript submission and processing at JNHRC.