Evolving horizons in renal angiomyolipoma: two decades of management strategies and clinical perspectives in a single institutional study.

IF 2.7 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Aging Male Pub Date : 2024-12-01 Epub Date: 2024-05-06 DOI:10.1080/13685538.2024.2346308

Ahmet Keles, Ayberk Iplikci, Ozgur Arikan, Meftun Culpan, Kursad Nuri Baydili, Ferhat Keser, Asif Yildirim

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引用次数: 0

Abstract

Objective: To assess various management options for renal angiomyolipoma (AML) to guide clinical practice.

Methods: A single center retrospectively reviewed an AML series from 2002 to 2022. The image reports and chart reviews of patients who received two abdominal scans at least 6 months between the first and last scans were assessed.

Results: A total of 203 patients with 209 tumors were identified and followed up for a median of 42.6 months. Active surveillance (AS) was the most frequently selected option (70.9% of cases). Interventions were required for 59 AMLs, of which 20 were treated with embolization, 29 with partial nephrectomy, 9 with radical nephrectomy, and 1 with radiofrequency (RF) ablation. The median size of the lesions at intervention was 5 cm. The average growth rate of the lesions was 0.12 cm/year, and there was a significant difference in the average growth rate of lesions ≤4 cm and those >4 cm (0.11 vs. 0.24 cm/year; p = 0.0046).

Conclusion: This series on AMLs confirms that lesions >4 cm do not require early intervention based on size alone. Appropriately selected cases of renal AML can be managed by AS.KEYWORDS: Angiomyolipoma; active surveillance; embolization; nephrectomy; nephron-sparing surgery.

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肾血管肌脂肪瘤的发展前景：一项单一机构研究中二十年的管理策略和临床观点。

目的：评估肾血管瘤（AML）的各种治疗方案，为临床实践提供指导：评估肾血管脂肪瘤（AML）的各种治疗方案，以指导临床实践：单个中心回顾性分析了2002年至2022年的AML系列。评估了接受两次腹部扫描的患者的图像报告和病历回顾，第一次扫描和最后一次扫描之间的间隔时间至少为 6 个月：结果：共发现203名患者，209个肿瘤，随访时间中位数为42.6个月。主动监测（AS）是最常见的选择（70.9%的病例）。59例急性髓系白血病需要介入治疗，其中20例采用栓塞治疗，29例采用肾部分切除术，9例采用根治性肾切除术，1例采用射频消融术。介入治疗时病灶的中位尺寸为 5 厘米。病变的平均生长速度为 0.12 厘米/年，≤4 厘米和大于 4 厘米的病变平均生长速度存在显著差异（0.11 vs. 0.24 厘米/年；P = 0.0046）：本系列急性髓系白血病病例证实，>4 厘米的病变不需要仅根据大小进行早期干预。关键字：血管肌脂肪瘤；主动监测；栓塞；肾切除术；保肾手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aging Male 医学-泌尿学与肾脏学

CiteScore

6.40

自引率

3.80%

发文量

审稿时长

>12 weeks

期刊介绍： The Aging Male , the official journal of the International Society for the Study of the Aging Male, is a multidisciplinary publication covering all aspects of male health throughout the aging process. The Journal is a well-recognized and respected resource for anyone interested in keeping up to date with developments in this field. It is published quarterly in one volume per year. The Journal publishes original peer-reviewed research papers as well as review papers and other appropriate educational material that provide researchers with an integrated perspective on this new, emerging specialty. Areas of interest include, but are not limited to: Diagnosis and treatment of late-onset hypogonadism Metabolic syndrome and related conditions Treatment of erectile dysfunction and related disorders Prostate cancer and benign prostate hyperplasia.