Feline infectious peritonitis: A comprehensive evaluation of clinical manifestations, laboratory diagnosis, and therapeutic approaches.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-12 eCollection Date: 2024-03-01 DOI:10.5455/javar.2024.k742

Wassamon Moyadee, Supita Sunpongsri, Kiattawee Choowongkomon, Sittiruk Roytrakul, Amonpun Rattanasrisomporn, Natthasit Tansakul, Jatuporn Rattanasrisomporn

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引用次数: 0

Abstract

Objective: This study aimed to investigate the clinical and laboratory characteristics of naturally occurring feline infectious peritonitis (FIP) and estimate the median survival time of FIP cats treated with prednisolone to guide further therapeutic planning.

Materials and methods: In this retrospective study, data from a total of 116 cats with effusion were fully recorded. Forty-five FIP-diagnosed cats were enrolled for analysis.

Results: The study findings indicate that FIP was a disease affecting cats aged 1-2 years and was highly prevalent among male cats. Clinical manifestations of FIP affected the digestive (60%), hematological (53.3%), respiratory (33.3%), neurological (6.7%), and ocular (4.4%) systems. Blood profiles revealed mild anemia, lymphopenia, thrombocytopenia, hypoalbuminemia, hyperglobulinemia, and an albumin to globulin ratio of 0.4. Fluid analysis and cytology of FIP cats demonstrated a transparent yellow fluid with a protein content of 6 gm/dl and a total nucleated cell count of approximately 5,000-10,000 cells. During the observation period, FIP cats treated with prednisolone exhibited a median survival time of 31 days.

Conclusion: Confirming FIP cases can be challenging; therefore, a tentative diagnosis of FIP must be made with care. This study provided practical diagnostic tools to diagnose FIP based on clinical signs and multiple abnormalities, which allowed for more efficient and rapid detection.

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猫传染性腹膜炎：全面评估临床表现、实验室诊断和治疗方法。

研究目的本研究旨在调查自然发生的猫传染性腹膜炎（FIP）的临床和实验室特征，并估计接受泼尼松龙治疗的 FIP 猫的中位存活时间，以指导进一步的治疗计划：在这项回顾性研究中，共全面记录了 116 只流脓猫的数据。结果：研究结果表明，FIP 在猫科动物中的发病率较高：研究结果表明，FIP是一种影响1-2岁猫咪的疾病，在公猫中发病率很高。FIP的临床表现影响消化系统（60%）、血液系统（53.3%）、呼吸系统（33.3%）、神经系统（6.7%）和眼部系统（4.4%）。血常规显示轻度贫血、淋巴细胞减少、血小板减少、低白蛋白血症、高球蛋白血症和白蛋白与球蛋白比值为 0.4。FIP 猫的体液分析和细胞学检查显示，体液呈透明黄色，蛋白质含量为 6 gm/dl，有核细胞总数约为 5,000-10,000 个。在观察期间，接受泼尼松龙治疗的 FIP 猫的中位存活时间为 31 天：结论：确诊 FIP 病例具有挑战性；因此，必须谨慎做出 FIP 的初步诊断。本研究提供了实用的诊断工具，可根据临床症状和多种异常情况诊断 FIP，从而提高检测效率和速度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.