Use of dynamic tissue system adhesive skin closure device and multi-tissue platform porcine xenograft to achieve primary closure after wide local excision of a melanoma.

IF 1.4 4区医学 Q3 DERMATOLOGY

Wounds : a compendium of clinical research and practice Pub Date : 2024-03-01

Jad F Zeitouni, Reagan Collins, Patricia Arledge, Yana Puckett, Catherine F Ronaghan

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引用次数: 0

Abstract

Background: Wide local excision with sentinel lymph node biopsy has been the standard of care for melanoma with a Breslow depth greater than 1 mm. Wide local excision with 1- to 2-cm margins can result in large wounds that cannot be primarily closed. Traditionally, management has included reconstruction with autologous flaps and skin grafting.

Case report: The authors of this case report achieved successful closure of a large posterior calf wound after 2-cm-wide local excision of the melanoma biopsy site in a 61-year-old male. The dermal lesion was a Clark level IV superficial spreading malignant melanoma with Breslow depth of 1.1 mm. Wound closure was achieved with a DTS adhesive skin closure device coupled with MTP xenograft powder as a healing adjunct.

Conclusion: The results of this patient's case indicate that DTS adhesive skin closure device should be considered as an additional option for the closure of large defects following wide local excision in the management of melanoma.

本刊更多论文

使用动态组织系统粘合皮肤闭合装置和多组织平台猪异种移植，实现黑色素瘤大范围局部切除术后的初次闭合。

背景：对于布氏深度大于 1 毫米的黑色素瘤，广泛局部切除并进行前哨淋巴结活检一直是标准的治疗方法。局部广泛切除术的边缘为 1 到 2 厘米，可能会造成无法进行基本闭合的大伤口。传统的治疗方法包括自体皮瓣重建和植皮：本病例报告的作者在对一名 61 岁男性的黑色素瘤活检部位进行 2 厘米宽的局部切除后，成功缝合了小腿后侧的大伤口。真皮层病变为克拉克 IV 级浅表扩散性恶性黑色素瘤，布氏深度为 1.1 毫米。使用 DTS 皮肤粘合闭合器和 MTP 异种移植粉作为愈合辅助工具，实现了伤口闭合：结论：该患者的病例结果表明，在治疗黑色素瘤时，应考虑将 DTS 皮肤粘合闭合器作为一种额外的选择，用于闭合大面积局部切除后的大面积缺损。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wounds : a compendium of clinical research and practice 医学-皮肤病学

CiteScore

1.50

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.