Identification of some variable parameters in serum of COVID-19 patients in comparison with control group.

Q3 Medicine
Ebtihal C Abbas, Mais M Salim, Ahmed C Abbas, Ahmed Z Alwaeli
{"title":"Identification of some variable parameters in serum of COVID-19 patients in comparison with control group.","authors":"Ebtihal C Abbas, Mais M Salim, Ahmed C Abbas, Ahmed Z Alwaeli","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The study intended to determine the correlation among coronavirus disease 2019 (COVID-19) infection and variable abnormalities in liver function test, lipids, and thyroid hormones. The study included 160 infected COVID-19 patients (80 females and 80 male) and 100 subjects as a control group (50 females and 50 males), attended the Al-Sader Medical City in Al-Najaf, Iraq during the period between January 2021 to October 2021. The patients' age ranged from 16-80 years old. Liver enzymes, lipid profile and thyroid hormone were tested. The results revealed a significant increase in liver function levels including alanine transaminase, aspartate aminotransferase, alkaline phosphatase, and Albumin (p < 0.05). Also, there was an increase in lipids levels including total cholesterol, low-density lipoprotein, and triglycerides. The result showed significant difference in levels of thyroid hormones triiodothyronine, thyroxine and thyroid stimulating hormone between COVID-19 infected patients and the control group. As well the antithyroid antibodies (thyroglobulin antibody, thyroid peroxidase antibody and thyrotropin receptor antibodies) were increased. There was a correlation between increasing thyroid hormones and their antibodies with infection by COVID-19. This study concluded that COVID-19 infection can induce disturbances in liver and thyroid function tests and changes in the lipid metabolism.</p>","PeriodicalId":39724,"journal":{"name":"The Egyptian journal of immunology / Egyptian Association of Immunologists","volume":"31 2","pages":"10-17"},"PeriodicalIF":0.0000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Egyptian journal of immunology / Egyptian Association of Immunologists","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

The study intended to determine the correlation among coronavirus disease 2019 (COVID-19) infection and variable abnormalities in liver function test, lipids, and thyroid hormones. The study included 160 infected COVID-19 patients (80 females and 80 male) and 100 subjects as a control group (50 females and 50 males), attended the Al-Sader Medical City in Al-Najaf, Iraq during the period between January 2021 to October 2021. The patients' age ranged from 16-80 years old. Liver enzymes, lipid profile and thyroid hormone were tested. The results revealed a significant increase in liver function levels including alanine transaminase, aspartate aminotransferase, alkaline phosphatase, and Albumin (p < 0.05). Also, there was an increase in lipids levels including total cholesterol, low-density lipoprotein, and triglycerides. The result showed significant difference in levels of thyroid hormones triiodothyronine, thyroxine and thyroid stimulating hormone between COVID-19 infected patients and the control group. As well the antithyroid antibodies (thyroglobulin antibody, thyroid peroxidase antibody and thyrotropin receptor antibodies) were increased. There was a correlation between increasing thyroid hormones and their antibodies with infection by COVID-19. This study concluded that COVID-19 infection can induce disturbances in liver and thyroid function tests and changes in the lipid metabolism.

确定 COVID-19 患者血清中的一些可变参数,并与对照组进行比较。
该研究旨在确定2019年冠状病毒病(COVID-19)感染与肝功能检测、血脂和甲状腺激素异常之间的相关性。研究对象包括 160 名感染 COVID-19 的患者(80 名女性和 80 名男性)和 100 名对照组受试者(50 名女性和 50 名男性),他们于 2021 年 1 月至 2021 年 10 月期间在伊拉克纳杰夫的 Al-Sader 医疗城就诊。患者年龄在 16-80 岁之间。对肝酶、血脂和甲状腺激素进行了检测。结果显示,丙氨酸转氨酶、天门冬氨酸氨基转移酶、碱性磷酸酶和白蛋白等肝功能水平明显升高(P < 0.05)。此外,血脂水平也有所增加,包括总胆固醇、低密度脂蛋白和甘油三酯。结果显示,COVID-19 感染者与对照组之间的甲状腺激素三碘甲状腺原氨酸、甲状腺素和促甲状腺激素水平存在明显差异。此外,抗甲状腺抗体(甲状腺球蛋白抗体、甲状腺过氧化物酶抗体和促甲状腺激素受体抗体)也有所增加。甲状腺激素及其抗体的增加与COVID-19感染之间存在相关性。这项研究得出结论,COVID-19感染可引起肝脏和甲状腺功能检测紊乱以及脂质代谢变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.20
自引率
0.00%
发文量
52
期刊介绍: Information not localized
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信