An open pilot trial of a behavioural intervention to reduce violence by young adults with early psychosis receiving treatment in an early intervention services setting: A protocol

IF 2.1 4区医学 Q3 PSYCHIATRY

Early Intervention in Psychiatry Pub Date : 2024-05-05 DOI:10.1111/eip.13543

Stephanie A. Rolin, Deirdre Caffrey, Megan G. Flores, Leah G. Pope, Jennifer Mootz, Iruma Bello, Ilana Nossel, Michael T. Compton, Barbara Stanley, Milton Wainberg, Lisa B. Dixon, Paul S. Appelbaum

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引用次数: 0

Abstract

Aims

Despite the public health impact of violence among young adults with psychosis, behavioural interventions to reduce the risk of engaging in violence remain rare. For young adults with early psychosis, cognitive behavioural therapy (CBT)-based psychotherapy has efficacy in reducing impairment and improving functioning. However, no CBT-based intervention to reduce violence has been formally adapted for young adults with early psychosis. This protocol outlines the first clinical trial of a behavioural intervention to reduce violence for young adults with early psychosis. This study is set in an early intervention services (EIS) setting and seeks to adapt and pilot Psychological Intervention for Complex PTSD and Schizophrenia-Spectrum Disorder (PICASSO), a CBT-based intervention, through an iterative process utilizing mixed-methods assessments.

Methods

All research will occur at OnTrackNY, the largest EIS program in the United States. This study will consist of an open pilot trial, with four EIS clinicians delivering the intervention to one to two EIS participants per round. In this mixed-methods study, both quantitative measures (acceptability, feasibility and hypothesized mediators of target outcome collected on a weekly basis) and qualitative interviews (with EIS clinicians at weeks 4, 8 and 12) will be conducted. Transcripts will be analyzed using thematic content analysis. Two to three rounds of iterative modifications are anticipated (n = 10–16 EIS participants total).

Results

Recruitment began in February 2024 and is expected to continue over a 9–12-month period.

Conclusions

Because violent behaviour causes interpersonal disruptions such as incarceration and increased caregiver burden, an innovative intervention to reduce violence risk could have broader health impact for this vulnerable population. Adapting the PICASSO intervention to the EIS setting will optimize its acceptability and feasibility by the intended target population.

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为减少在早期干预服务机构接受治疗的患有早期精神病的年轻成年人的暴力行为而进行的行为干预公开试点试验：方案。

目的：尽管暴力对年轻的成年精神病患者的公共健康造成了影响，但通过行为干预来降低参与暴力的风险仍然很少见。对于患有早期精神病的年轻人来说，以认知行为疗法（CBT）为基础的心理疗法在减少损伤和改善功能方面具有疗效。然而，目前还没有任何基于 CBT 的减少暴力干预措施被正式调整用于患有早期精神病的年轻人。本方案概述了针对患有早期精神病的年轻成年人进行的第一项减少暴力的行为干预临床试验。本研究以早期干预服务（EIS）为背景，旨在通过使用混合方法评估的迭代过程，调整并试点基于 CBT 的干预措施--复杂创伤后应激障碍和精神分裂症谱系障碍心理干预（PICASSO）：所有研究都将在美国最大的 EIS 项目 OnTrackNY 进行。本研究将包括一项公开试点试验，由四名 EIS 临床医生每轮向一至两名 EIS 参与者提供干预措施。在这项混合方法研究中，将同时进行定量测量（每周收集目标结果的可接受性、可行性和假设的中介因素）和定性访谈（在第 4、8 和 12 周对 EIS 临床医生进行访谈）。将采用专题内容分析法对记录誊本进行分析。预计将进行两到三轮反复修改（n = 10-16 名 EIS 参与者）：招募工作于 2024 年 2 月开始，预计将持续 9-12 个月：由于暴力行为会造成人际关系的混乱，如监禁和增加照顾者的负担，因此减少暴力风险的创新干预措施可能会对这一弱势群体产生更广泛的健康影响。将 PICASSO 干预措施调整到 EIS 环境中，将优化目标人群的接受度和可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Early Intervention in Psychiatry 医学-精神病学

CiteScore

4.80

自引率

5.00%

发文量

112

审稿时长

6-12 weeks

期刊介绍： Early Intervention in Psychiatry publishes original research articles and reviews dealing with the early recognition, diagnosis and treatment across the full range of mental and substance use disorders, as well as the underlying epidemiological, biological, psychological and social mechanisms that influence the onset and early course of these disorders. The journal provides comprehensive coverage of early intervention for the full range of psychiatric disorders and mental health problems, including schizophrenia and other psychoses, mood and anxiety disorders, substance use disorders, eating disorders and personality disorders. Papers in any of the following fields are considered: diagnostic issues, psychopathology, clinical epidemiology, biological mechanisms, treatments and other forms of intervention, clinical trials, health services and economic research and mental health policy. Special features are also published, including hypotheses, controversies and snapshots of innovative service models.