Evaluation of Clinical, Laboratory, and Radiologic Findings of Pulmonary and Extrapulmonary Involvement in Sarcoidosis.

Q3 Medicine
Tanaffos Pub Date : 2023-03-01
Maryam Mobini, Masoud Aliyali, Siavash Abedi, Fatemeh Niksolat, Reza Ali Mohammadpour, Yasaman Salehi
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引用次数: 0

Abstract

Background: Sarcoidosis is a systemic disease with unknown etiology that is characterized by the presence of granuloma in various organs with diverse pulmonary and extrapulmonary manifestations. Regarding differences in the presentation of sarcoidosis in different geographical areas, the present study aimed to determine clinical, laboratory, and radiologic findings of patients with sarcoidosis in the north of Iran.

Materials and methods: In a cross-sectional study, patients with sarcoidosis were enrolled, and demographic data in addition to disease manifestations including clinical, laboratory, and imaging findings were recorded.

Results: A total of 58 patients with sarcoidosis were enrolled in the study. The mean age and disease duration were 51.10±10.2 and 3.07±2.7 years, respectively. 62.1% of patients were female. Clinical manifestations were: cough and dyspnea (55.2%), fever and weight loss (11%), arthritis (15.5%), dermatologic presentation (15.5%), and ophthalmic involvement (17.2 %). Abnormalities in liver, renal, and calcium levels are found in approximately 1-8% of cases. The ACE level was increased in 56.9 % of patients, especially in those who presented in summer and autumn. Chest CT abnormalities were found in 94.8 % of patients, more predominantly hilar and paratracheal lymphadenopathy in 84.5% and 74.1%, respectively.

Conclusion: Although sarcoidosis presents with varying clinical, radiological, and laboratory features, knowledge of its epidemiology and the incidence of these features in different populations can aid in its diagnosis in a particular geographic area.

肉样瘤病肺部和肺外受累的临床、实验室和放射学检查结果评估》(Evaluation of Clinical, Laboratory, and Radologic Findings of Pulmonary and Extrapmonary Involvement in Sarcoidosis)。
背景:肉样瘤病是一种病因不明的全身性疾病,其特点是在各种器官中出现肉芽肿,并伴有多种肺部和肺外表现。鉴于肉样瘤病在不同地理区域的表现形式存在差异,本研究旨在确定伊朗北部肉样瘤病患者的临床、实验室和放射学检查结果:在一项横断面研究中,对肉样瘤病患者进行了登记,并记录了人口统计学数据以及包括临床、实验室和影像学检查结果在内的疾病表现:结果:共有 58 名肉样瘤病患者参与了研究。平均年龄(51.10±10.2)岁,平均病程(3.07±2.7)年。62.1%的患者为女性。临床表现为:咳嗽和呼吸困难(55.2%)、发热和体重减轻(11%)、关节炎(15.5%)、皮肤病(15.5%)和眼部受累(17.2%)。约有 1-8%的病例出现肝脏、肾脏和血钙水平异常。56.9%的患者 ACE 水平升高,尤其是夏秋季发病的患者。94.8%的患者发现胸部 CT 异常,其中以肺门和气管旁淋巴结病变为主,分别占 84.5%和 74.1%:尽管肉样瘤病的临床、放射学和实验室特征各不相同,但了解其流行病学和这些特征在不同人群中的发病率有助于特定地区的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Tanaffos
Tanaffos Medicine-Critical Care and Intensive Care Medicine
CiteScore
1.10
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