Investigating the Effects of Level-Specific CE-Chirp on Auditory Brainstem Response Waves in Normal Hearing Infants.

IF 1.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Malaysian Journal of Medical Sciences Pub Date : 2024-04-01 Epub Date: 2024-04-23 DOI:10.21315/mjms2024.31.2.7

Norashikin Chahed, Ahmad Aidil Arafat Dzulkarnain, Saiful Adli Jamaluddin

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引用次数: 0

Abstract

Background: Auditory brainstem response (ABR) to the level-specific (LS) CE-Chirp has been reported to provide optimum neural synchrony along cochlear partitions, theoretically improving ABR waveform resolution. Despite this promising finding, limited studies have been conducted to contrast the results between LS CE-Chirp and Click stimuli. The current study aimed to compare the results of ABR between the two stimuli (Click and LS CE-Chirp).

Method: Sixty-seven normal-hearing infants, both with and without risk factors, aged less than 7 months old, participated in this study. The ABR test was conducted at 70 dBnHL using 33.3 stimulus repetition rates with both Click and LS CE-Chirp stimuli. The signal averaging was stopped at a maximum fixed signal average of 2,500 sweeps. Data were statistically compared between the two stimuli using the Wilcoxon signed-rank test.

Results: The waves I and V ABRs elicited by LS CE-Chirp exhibited significantly larger amplitudes than the Click stimulus. However, the amplitude of wave III and absolute latencies were similar in both stimuli at a supra-threshold level.

Conclusion: LS CE-Chirp has the advantage of larger amplitudes than the ABR from Click at the supra-threshold level (70 dBnHL) in normal-hearing infants.

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研究特定水平的 CE-Chirp 对正常听力婴儿听觉脑干反应波的影响

背景：据报道，对特定水平（LS）CE-Chirp 的听性脑干反应（ABR）可提供沿耳蜗分区的最佳神经同步，理论上可提高 ABR 波形分辨率。尽管这一发现很有希望，但对 LS CE-Chirp 和 Click 刺激结果进行对比的研究还很有限。本研究旨在比较两种刺激（Click 和 LS CE-Chirp）之间的 ABR 结果：方法：67 名听力正常的 7 个月以下婴儿参加了本研究，包括有风险因素和无风险因素的婴儿。ABR 测试在 70 dBnHL 的条件下进行，使用 33.3 的刺激重复率，同时使用 Click 和 LS CE-Chirp 刺激。信号平均值在 2,500 次扫描的最大固定信号平均值时停止。使用 Wilcoxon 符号秩检验对两种刺激之间的数据进行统计比较：结果：LS CE-Chirp 引起的 I 波和 V 波 ABR 的振幅明显大于 Click 刺激。然而，在阈值以上水平，两种刺激引起的第 III 波振幅和绝对潜伏期相似：结论：在阈上水平（70 dBnHL），LS CE-Chirp 的优势在于其振幅大于 Click 对正常听力婴儿的 ABR。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Malaysian Journal of Medical Sciences MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

2.70

自引率

0.00%

发文量

审稿时长

9 weeks

期刊介绍： The Malaysian Journal of Medical Sciences (MJMS) is a peer-reviewed, open-access, fully online journal that is published at least six times a year. The journal’s scope encompasses all aspects of medical sciences including biomedical, allied health, clinical and social sciences. We accept high quality papers from basic to translational research especially from low & middle income countries, as classified by the United Nations & World Bank (https://datahelpdesk.worldbank.org/knowledgebase/ articles/906519), with the aim that published research will benefit back the bottom billion population from these countries. Manuscripts submitted from developed or high income countries to MJMS must contain data and information that will benefit the socio-health and bio-medical sciences of these low and middle income countries. The MJMS editorial board consists of internationally regarded clinicians and scientists from low and middle income countries.