Systemic treatment and surgical intervention in inflammatory Terrien disease.

IF 1 Q4 OPHTHALMOLOGY
Taiwan Journal of Ophthalmology Pub Date : 2024-03-15 eCollection Date: 2024-01-01 DOI:10.4103/tjo.TJO-D-23-00176
Francisco Arnalich-Montiel
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引用次数: 0

Abstract

This case report presents a unique instance of a 55-year-old male patient exhibiting features of both Terrien marginal degeneration (TMD) and Fuchs' superficial marginal keratitis. Characterized by peripheral corneal thinning vascularization, and a pseudopterygium, the patient experienced recurrent photophobia, redness, and tearing over 15 years. This case challenges the traditional distinction between TMD and Fuchs' superficial marginal keratitis, suggesting a potential common underlying disorder. Mycophenolate mofetil provided a partial response, while pseudopterygium removal led to sustained remission, emphasizing its therapeutic significance. This case highlights the first documented use of mycophenolate in TMD and supports the notion of shared vasculitic origins between TMD and Fuchs' keratitis, raising intriguing questions about targeted therapeutic interventions.

炎症性特里恩病的系统治疗和手术干预。
本病例报告介绍了一名 55 岁男性患者的独特病例,该患者同时具有特里恩角膜缘变性(Terrien marginal degeneration,TMD)和福氏浅缘角膜炎的特征。患者的特征是角膜周边血管变细和假性翼状胬肉,15 年来反复出现畏光、发红和流泪症状。该病例对 TMD 和 Fuchs 表浅边缘角膜炎之间的传统区别提出了质疑,提示两者可能存在共同的潜在疾病。霉酚酸酯可缓解部分症状,而切除假性翼状胬肉则可使症状持续缓解,这突出了假性翼状胬肉的治疗意义。该病例是首次在 TMD 中使用霉酚酸酯的记录,支持了 TMD 和 Fuchs 角膜炎之间有共同的血管病变起源的观点,提出了有关针对性治疗干预的有趣问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.80
自引率
9.10%
发文量
68
审稿时长
19 weeks
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