Evaluation of articular cartilage degeneration in patients with osteonecrosis of the femoral head using T2 mapping magnetic resonance imaging.

IF 1.8 4区医学 Q3 RHEUMATOLOGY

Modern Rheumatology Pub Date : 2024-10-15 DOI:10.1093/mr/roae020

Hiroki Kaneta, Takeshi Shoji, Hideki Shozen, Shinichi Ueki, Nobuo Adachi

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引用次数: 0

Abstract

Objectives: To evaluate and characterise articular cartilage degeneration in patients with osteonecrosis of the femoral head (ONFH) using T2 mapping magnetic resonance imaging.

Methods: We reviewed 35 patients with ONFH (20 males and 15 females, mean age: 45.7 ± 12.9 years) without obvious cartilage abnormalities on plain magnetic resonance imaging (ONFH group) and 25 healthy volunteers (9 males and 16 females, mean age: 42.9 ± 5.8 years) (control group). All patients underwent T2 mapping magnetic resonance imaging after ONFH onset. The region of interest was defined as the weight-bearing portion of the articular cartilage in the femoral head and acetabulum in the coronal view.

Results: The T2 values of the articular cartilage of the acetabulum and femoral head, including necrotic and normal regions, were significantly higher in the ONFH group than those in the control group. These T2 values of the acetabulum and femoral head in Stages 3A and 2 were significantly higher in the ONFH group than those in the control group.

Conclusions: The articular cartilage of the acetabulum and femoral head can deteriorate after the onset of ONFH, which may affect the natural history of ONFH and ONFH treatment. Our findings suggest the need for early intervention in joint preservation surgery.

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利用 T2 映射磁共振成像评估股骨头坏死患者的关节软骨退化情况。

目的使用T2映射磁共振成像（MRI）评估股骨头坏死（ONFH）患者的关节软骨退化情况并确定其特征：我们对 35 名（男 20 名，女 15 名，平均年龄（45.7±12.9）岁）普通 MRI 检查无明显软骨异常的股骨头坏死患者（股骨头坏死组）和 25 名（男 9 名，女 16 名，平均年龄（42.9±5.8）岁）健康志愿者（对照组）进行了回顾性研究。所有患者都在 ONFH 发病后接受了 T2 映射 MRI 检查。研究区域定义为股骨头和髋臼冠状面上关节软骨的负重部分：结果：髋臼和股骨头关节软骨（包括坏死区和正常区）的 T2 值在 ONFH 组明显高于对照组。髋臼和股骨头在3A期和2期的T2值明显高于对照组：结论：髋臼和股骨头的关节软骨在ONFH发病后可能会恶化，这可能会影响ONFH的自然史和ONFH的治疗。我们的研究结果表明，有必要对关节保存手术进行早期干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Modern Rheumatology RHEUMATOLOGY-

CiteScore

4.90

自引率

9.10%

发文量

146

审稿时长

1.5 months

期刊介绍： Modern Rheumatology publishes original papers in English on research pertinent to rheumatology and associated areas such as pathology, physiology, clinical immunology, microbiology, biochemistry, experimental animal models, pharmacology, and orthopedic surgery. Occasional reviews of topics which may be of wide interest to the readership will be accepted. In addition, concise papers of special scientific importance that represent definitive and original studies will be considered. Modern Rheumatology is currently indexed in Science Citation Index Expanded (SciSearch), Journal Citation Reports/Science Edition, PubMed/Medline, SCOPUS, EMBASE, Chemical Abstracts Service (CAS), Google Scholar, EBSCO, CSA, Academic OneFile, Current Abstracts, Elsevier Biobase, Gale, Health Reference Center Academic, OCLC, SCImago, Summon by Serial Solutions