Global, regional, and national burden of atrial fibrillation/flutter related to metabolic risks over three decades: estimates from the global burden of disease study 2019.

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2024-08-08 DOI:10.1093/ehjqcco/qcae033

Xi Jiang, Jianen Ling, Qingsong Xiong, Weijie Chen, Lili Zou, Zhiyu Ling

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引用次数: 0

Abstract

Aims: Atrial fibrillation/atrial flutter (AF/AFL) remains a significant public health concern on a global scale, with metabolic risks playing an increasingly prominent role. This study aimed to investigate comprehensive epidemiological data and trends concerning the metabolic risks related-AF/AFL burden based on the data from the Global Burden of Disease study in 2019.

Methods and results: The analysis of disease burden focused on numbers, age-standardized rates of deaths, disability-adjusted life years (DALYs), and estimated annual percentage change, while considering factors of age, sex, sociodemographic index (SDI), and locations. In 2019, there was a culmination of 137 179 deaths and 4 099 146 DALYs caused by metabolic risks related-AF/AFL worldwide, with an increase of 162.95% and 120.30%, respectively from 1990. High and high-middle SDI regions predominantly carried the burden of AF/AFL associated with metabolic risks, while a shift towards lower SDI regions had been occurring. Montenegro had the highest recorded death rate (7.6 per 100 000) and DALYs rate (146.3 per 100 000). An asymmetrically inverted V-shaped correlation was found between SDI and deaths/DALYs rates. Moreover, females and the elderly exhibited higher AF/AFL burdens, and young adults (over 40 years old) also experienced an annual increase.

Conclusion: The global AF/AFL burden related to metabolic risks has significantly increased over the past three decades, with considerable spatiotemporal, gender-based, and age-related heterogeneity. These findings shed valuable light on the trends in the burden of metabolic risks related-AF/AFL and offered insights into corresponding strategies.

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三十年来与代谢风险相关的全球、地区和国家心房颤动/扑动负担：2019 年全球疾病负担研究的估计值。

目的：心房颤动/心房扑动（AF/AFL）仍然是全球范围内的重大公共卫生问题，其中代谢风险的作用日益突出。本研究旨在根据 2019 年全球疾病负担（GBD）研究的数据，调查与代谢风险相关的房颤/房扑负担的综合流行病学数据和趋势：疾病负担分析的重点是死亡人数、年龄标准化死亡率（ASR）、残疾调整生命年（DALYs）和估计年度百分比变化（EAPC），同时考虑年龄、性别、社会人口指数（SDI）和地点等因素。2019 年，全球因与代谢风险相关的 AF/AFL 导致的死亡人数为 137 179 人，DALYs 为 4 099 146 人，与 1990 年相比分别增长了 162.95% 和 120.30%。与代谢风险相关的心房颤动/心力衰竭的负担主要由高、中SDI地区承担，而向低SDI地区转移的趋势正在发生。黑山的死亡率（每 100 000 人中有 7.6 人）和残疾调整寿命年数（每 100 000 人中有 146.3 人）都是最高的。在 SDI 和死亡率/残疾调整寿命年数之间发现了不对称的倒 V 型相关关系。此外，女性和老年人的心房颤动/心力衰竭负担较重，年轻成年人（40 岁以上）的心房颤动/心力衰竭负担也在逐年增加：结论：过去三十年来，与代谢风险相关的全球心房颤动/心力衰竭负担显著增加，并具有相当大的时空、性别和年龄异质性。这些发现揭示了与代谢风险相关的心房颤动/心力衰竭负担的趋势，并为相应的策略提供了启示。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.