Effect of water temperature on the anesthetic effects of alfaxalone in carp (Cyprinus carpio).

IF 1.5 Q3 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Journal of Advanced Veterinary and Animal Research Pub Date : 2024-03-12 eCollection Date: 2024-03-01 DOI:10.5455/javar.2024.k743

Kenichi Maeda, Daiki Hotta, Takuma Matsui, Satomi Iwai, Shozo Okanao

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引用次数: 0

Abstract

Objective: To evaluate the effect of water temperature on intramuscular injected alfaxalone anesthesia in carp (Cyprinus carpio).

Materials and methods: Six healthy adult carp (C. carpio) were intramuscularly injected with alfaxalone (2.5, 5.0, or 7.5 mg/kg) at normal water temperature (25°C) and at low water temperature (2.5 mg/kg, 15°C). The respiratory rate, heart rate (HR), and anesthesia depth (AD) were evaluated every 5 min for 30 min after administration and every 1 h after 60 min after injection.

Results: The respiratory and HRs did not change significantly upon alfaxalone injection, regardless of dose. However, a dose-dependent increase in AD scores was observed. Furthermore, 2.5 mg/kg alfaxalone injected in 15°C water showed an almost equal anesthetic effect to that of 5.0 mg/kg alfaxalone in 25°C water.

Conclusion: Alfaxalone is readily available, and its anesthetic effect in carp was enhanced by lowering water temperature, illustrating the possibility of intramuscular injection of alfaxalone in fish.

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水温对阿法沙酮在鲤鱼体内麻醉效果的影响。

目的：评估水温对鲤鱼肌肉注射阿法沙酮麻醉的影响：评估水温对鲤鱼肌肉注射阿法沙酮麻醉的影响：在正常水温（25°C）和低水温（2.5 毫克/千克，15°C）下，给 6 条健康成年鲤鱼肌肉注射阿法沙酮（2.5、5.0 或 7.5 毫克/千克）。给药后 30 分钟内每隔 5 分钟评估一次呼吸频率、心率和麻醉深度，注射后 60 分钟后每隔 1 小时评估一次麻醉深度：结果：注射阿法沙酮后，无论剂量大小，呼吸频率和心率均无明显变化。然而，AD评分的增加与剂量有关。此外，在15°C水中注射2.5毫克/千克阿法沙酮与在25°C水中注射5.0毫克/千克阿法沙酮的麻醉效果几乎相同：结论：阿法沙隆很容易获得，降低水温可增强其对鲤鱼的麻醉效果，这说明了在鱼类肌肉注射阿法沙隆的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Advanced Veterinary and Animal Research Veterinary-Veterinary (all)

CiteScore

2.70

自引率

7.10%

发文量

审稿时长

6 weeks

期刊介绍： Journal of Advanced Veterinary and Animal Research (JAVAR) - is an open access, international, peer-reviewed, quarterly, highly-indexed scientific journal publishing original research findings and reviews on all aspects of veterinary and animal sciences. Basic and applied researches on- - Anatomy & histology - Animal health economics - Animal nutrition - Animal reproduction - Animal science - Antimicrobial resistance (AMR) - Biochemistry - Biotechnology - Dairy science - Epidemiology - Food hygiene and technology - Genetics and breeding - Immunology - Microbiology - Parasitology - Pathology - Pharmacology & toxicology - Physiology - Poultry science - Preventive veterinary medicine - Public health - Surgery & obstetrics - Veterinary extension studies - Wildlife & aquatic medicine - Zoo animal medicine.