Neighborhood disadvantage is associated with working memory and hippocampal volumes among older adults.

IF 1.6 4区心理学 Q3 PSYCHOLOGY, DEVELOPMENTAL

Aging, Neuropsychology, and Cognition Pub Date : 2024-04-24 DOI:10.1080/13825585.2024.2345926

Regina S Wright, Alexa C Allan, Alyssa A Gamaldo, Adrienne A Morgan, Anna K Lee, Guray Erus, Christos Davatzikos, Desirée C Bygrave

{"title":"Neighborhood disadvantage is associated with working memory and hippocampal volumes among older adults.","authors":"Regina S Wright, Alexa C Allan, Alyssa A Gamaldo, Adrienne A Morgan, Anna K Lee, Guray Erus, Christos Davatzikos, Desirée C Bygrave","doi":"10.1080/13825585.2024.2345926","DOIUrl":null,"url":null,"abstract":"It is not well understood how neighborhood disadvantage is associated with specific domains of cognitive function and underlying brain health within older adults. Thus, the objective was to examine associations between neighborhood disadvantage, brain health, and cognitive performance, and examine whether associations were more pronounced among women. The study included 136 older adults who underwent cognitive testing and MRI. Neighborhood disadvantage was characterized using the Area Deprivation Index (ADI). Descriptive statistics, bivariate correlations, and multiple regressions were run. Multiple regressions, adjusted for age, sex, education, and depression, showed that higher ADI state rankings (greater disadvantage) were associated with poorer working memory performance (p < .01) and lower hippocampal volumes (p < .01), but not total, frontal, and white matter lesion volumes, nor visual and verbal memory performance. There were no significant sex interactions. Findings suggest that greater neighborhood disadvantage may play a role in working memory and underlying brain structure.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11499292/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aging, Neuropsychology, and Cognition","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/13825585.2024.2345926","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PSYCHOLOGY, DEVELOPMENTAL","Score":null,"Total":0}

引用次数: 0

Abstract

It is not well understood how neighborhood disadvantage is associated with specific domains of cognitive function and underlying brain health within older adults. Thus, the objective was to examine associations between neighborhood disadvantage, brain health, and cognitive performance, and examine whether associations were more pronounced among women. The study included 136 older adults who underwent cognitive testing and MRI. Neighborhood disadvantage was characterized using the Area Deprivation Index (ADI). Descriptive statistics, bivariate correlations, and multiple regressions were run. Multiple regressions, adjusted for age, sex, education, and depression, showed that higher ADI state rankings (greater disadvantage) were associated with poorer working memory performance (p < .01) and lower hippocampal volumes (p < .01), but not total, frontal, and white matter lesion volumes, nor visual and verbal memory performance. There were no significant sex interactions. Findings suggest that greater neighborhood disadvantage may play a role in working memory and underlying brain structure.

查看原文本刊更多论文

邻里关系不利与老年人的工作记忆和海马体积有关。

目前还不太清楚邻里劣势与老年人认知功能的特定领域和潜在的大脑健康之间的关系。因此，这项研究的目的是考察邻里劣势、大脑健康和认知表现之间的关联，并考察这种关联在女性中是否更为明显。这项研究包括 136 名接受认知测试和核磁共振成像的老年人。使用地区贫困指数（ADI）来描述邻里劣势。研究采用了描述性统计、二元相关和多元回归等方法。根据年龄、性别、教育程度和抑郁程度进行调整后得出的多元回归结果显示，ADI 州排名越高（贫困程度越高），工作记忆能力越差（P P

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Aging, Neuropsychology, and Cognition Multiple-

CiteScore

4.30

自引率

5.30%

发文量

期刊介绍： The purposes of Aging, Neuropsychology, and Cognition are to (a) publish research on both the normal and dysfunctional aspects of cognitive development in adulthood and aging, and (b) promote the integration of theories, methods, and research findings between the fields of cognitive gerontology and neuropsychology. The primary emphasis of the journal is to publish original empirical research. Occasionally, theoretical or methodological papers, critical reviews of a content area, or theoretically relevant case studies will also be published.