Screening of amino acids as a safe energy source for isolated rat pancreatic acini.

IF 1.7 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Pancreas Pub Date : 2024-05-01 DOI:10.1097/mpa.0000000000002350

Anastasiia M Zub, Bohdan O Manko, Volodymyr V Manko

引用次数: 0

Abstract

Amino acids play an essential role in protein synthesis, metabolism and survival of pancreatic acini. Adequate nutritional support is important for acute pancreatitis treatment. However, high concentrations of arginine and lysine may induce acute pancreatitis. The study aimed to identify the most suitable L-amino acids as safe energy sources for pancreatic acinar cells.

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筛选氨基酸作为离体大鼠胰腺皮质的安全能量来源。

氨基酸在蛋白质合成、新陈代谢和胰腺棘突存活方面发挥着重要作用。充足的营养支持对急性胰腺炎的治疗非常重要。然而，高浓度的精氨酸和赖氨酸可能会诱发急性胰腺炎。本研究旨在确定最适合作为胰腺尖细胞安全能量来源的 L- 氨基酸。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pancreas 医学-胃肠肝病学

CiteScore

4.70

自引率

3.40%

发文量

289

审稿时长

1 months

期刊介绍： Pancreas provides a central forum for communication of original works involving both basic and clinical research on the exocrine and endocrine pancreas and their interrelationships and consequences in disease states. This multidisciplinary, international journal covers the whole spectrum of basic sciences, etiology, prevention, pathophysiology, diagnosis, and surgical and medical management of pancreatic diseases, including cancer.