Nullification of GFTs fortifies bioactive folates in foxtail millet

IF 9.3 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Integrative Plant Biology Pub Date : 2024-05-02 DOI:10.1111/jipb.13665

Jianzhou Pang, Wei Zhang, Yanyan Zhang, Shihui Zhang, Yannan Wang, Hui Zhi, Chunyi Zhang, Qiuju Liang, Xianmin Diao

引用次数: 0

Abstract

In foxtail millet (Setaria italica), knockout of the glutamate formiminotransferases SiGFT1 and 2 increased the accumulation of bioactive folates to approximately four times the level of wild-type plants and decreased levels of the bioinactive oxidation product MeFox by 95%, thus providing a promising route for folate biofortification in cereal crops.

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GFTs 的无效化强化了狐尾黍中的生物活性叶酸

在狐尾黍（Setaria italica）中，谷氨酸酰亚胺转移酶 SiGFT1 和 2 的基因敲除使生物活性叶酸的积累增加到野生型植物的约四倍，并使生物活性氧化产物 MeFox 的水平降低了 95%，从而为谷类作物的叶酸生物强化提供了一条可行的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Integrative Plant Biology 生物-生化与分子生物学

CiteScore

18.00

自引率

5.30%

发文量

220

审稿时长

3 months

期刊介绍： Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.