Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair

IF 26.6 1区材料科学 Q1 Engineering

Nano-Micro Letters Pub Date : 2024-04-30 DOI:10.1007/s40820-024-01392-7

Yao Xiao, Zaijin Tao, Yufeng Ju, Xiaolu Huang, Xinshu Zhang, Xiaonan Liu, Pavel A. Volotovski, Chao Huang, Hongqi Chen, Yaozhong Zhang, Shen Liu

引用次数: 0

Abstract

The anti-adhesion effect of polylactic acid (PLA) membrane with diamond-like carbon (DLC) depositing is 44.72%, enhanced by 23.11% compared to PLA.
DLC deposited on PLA membranes has been shown to effectively reduce the levels of reactive oxygen species, leading to a decrease in the expression of pro-inflammatory cytokines within peritendinous adhesion tissue.
DLC decelerates PLA biodegradation and lactic production, which reduces the number of CD68⁺CD206⁺ macrophages within peritendinous adhesion tissue.

Abstract Image

查看原文本刊更多论文

在聚乳酸膜表面沉积类金刚石碳以防止肌腱修复过程中的粘连形成

沉积了类金刚石碳（DLC）的聚乳酸（PLA）膜的抗粘连效果为44.72%，与PLA相比提高了23.11%。事实证明，在聚乳酸膜上沉积类金刚石碳可有效降低活性氧水平，从而减少腱周粘连组织中促炎细胞因子的表达。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nano-Micro Letters NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

32.60

自引率

4.90%

发文量

981

审稿时长

1.1 months

期刊介绍： Nano-Micro Letters is a peer-reviewed, international, interdisciplinary, and open-access journal published under the SpringerOpen brand. Nano-Micro Letters focuses on the science, experiments, engineering, technologies, and applications of nano- or microscale structures and systems in various fields such as physics, chemistry, biology, material science, and pharmacy.It also explores the expanding interfaces between these fields. Nano-Micro Letters particularly emphasizes the bottom-up approach in the length scale from nano to micro. This approach is crucial for achieving industrial applications in nanotechnology, as it involves the assembly, modification, and control of nanostructures on a microscale.