Dynamic hyperinflation on exercise and its relationship with lung mechanics at rest in adults with central obesity

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-28 DOI:10.1016/j.resp.2024.104270

Carlos Eduardo Santos , Luis Felipe da Fonseca Reis , Sidney Fernandes da Silva , Iasmim Maria Pereira Pinto Fonseca , Wellington de Oliveira Pereira , Laura Franco Pessoa , Paolo Blanco Villela , Agnaldo José Lopes

{"title":"Dynamic hyperinflation on exercise and its relationship with lung mechanics at rest in adults with central obesity","authors":"Carlos Eduardo Santos , Luis Felipe da Fonseca Reis , Sidney Fernandes da Silva , Iasmim Maria Pereira Pinto Fonseca , Wellington de Oliveira Pereira , Laura Franco Pessoa , Paolo Blanco Villela , Agnaldo José Lopes","doi":"10.1016/j.resp.2024.104270","DOIUrl":null,"url":null,"abstract":"<div><p>This study aimed to evaluate the presence of dynamic hyperinflation (DH) during the Glittre-ADL test (TGlittre) coupled to the dynamic ventilation measurements in people with central obesity (pwCO) and to correlate it with lung mechanics at rest. Sixty-four pwCO underwent TGlittre and the following resting lung function tests: spirometry and impulse oscillometry system (IOS). On TGlittre, 22 participants presented DH at the end of the test (DH group), while 42 did not present DH (NDH group). Body mass index (BMI), waist circumference (WC), and hip circumference (HC) were higher in the DH group than in the NDH group. IOS abnormalities were more common in the DH group compared to the NDH group. TGlittre time significantly correlated with BMI, WC, waist-to-hip ratio (WHR), and neck circumference (NC). Delta inspiratory capacity correlated significantly with WC, HC, NC, and resonance frequency measured by IOS. Thus, pwCO perform worse on TGlittre, and DH is frequent in those with higher anthropometric indices and worse lung mechanics.</p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1569904824000636","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

This study aimed to evaluate the presence of dynamic hyperinflation (DH) during the Glittre-ADL test (TGlittre) coupled to the dynamic ventilation measurements in people with central obesity (pwCO) and to correlate it with lung mechanics at rest. Sixty-four pwCO underwent TGlittre and the following resting lung function tests: spirometry and impulse oscillometry system (IOS). On TGlittre, 22 participants presented DH at the end of the test (DH group), while 42 did not present DH (NDH group). Body mass index (BMI), waist circumference (WC), and hip circumference (HC) were higher in the DH group than in the NDH group. IOS abnormalities were more common in the DH group compared to the NDH group. TGlittre time significantly correlated with BMI, WC, waist-to-hip ratio (WHR), and neck circumference (NC). Delta inspiratory capacity correlated significantly with WC, HC, NC, and resonance frequency measured by IOS. Thus, pwCO perform worse on TGlittre, and DH is frequent in those with higher anthropometric indices and worse lung mechanics.

查看原文本刊更多论文

中心性肥胖症成人运动时的动态过度充气及其与静态肺力学的关系

本研究旨在评估中心性肥胖症患者（pwCO）在进行格利特-ADL 测试（TGlittre）和动态通气测量时是否存在动态过度充气（DH），并将其与静息状态下的肺力学相关联。64 名中心性肥胖症患者接受了 TGlittre 和以下静息肺功能测试：肺活量和脉冲振荡测量系统（IOS）。在 TGlittre 测试中，22 名参与者在测试结束时出现 DH（DH 组），42 名参与者没有出现 DH（NDH 组）。DH组的体重指数（BMI）、腰围（WC）和臀围（HC）均高于NDH组。与 NDH 组相比，DH 组的 IOS 异常更为常见。TGlittre时间与体重指数（BMI）、腹围（WC）、腰臀比（WHR）和颈围（NC）呈显著相关。德尔塔吸气量与体重指数、腰臀比、颈围和 IOS 测量的共振频率明显相关。因此，pwCO 在 TGlittre 中的表现较差，而 DH 频繁出现在人体测量指数较高和肺力学较差的人群中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.