Family dysfunction, stressful life events, and mental health problems across development in the offspring of parents with an affective disorder

IF 6.5 1区 医学 Q1 PSYCHIATRY
Tiffany Resendes, Mark A. Ellenbogen, Albertine J. Oldehinkel
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引用次数: 0

Abstract

Background

Offspring of parents with affective disorders (OAD) are at risk of developing a wide range of mental disorders. Deficits in the rearing environment and high levels of stress are well-known risk factors for negative outcomes in OAD. Building on prior research, we aim to examine the longitudinal relationships between family dysfunction, stressful life events, and mental health in OAD and control offspring of parents with no affective disorder. In the present study, we hypothesized that high levels of family dysfunction would be associated with more internalizing and externalizing problems across time in OAD than in controls, and that family dysfunction would mediate the relationship between stressful life events in adolescence and poor mental health in adulthood, particularly in OAD.

Methods

As part of the TRacking Adolescents' Lives Survey (TRAILS), 2230 participants (51% female, Mage = 11.1 years, SD = 0.6, at baseline) and their parents completed measures across six time points, spanning 15 years. Mental health, family dysfunction, and stressful life events were assessed with the Youth and Adult Self-Report, Family Assessment Device, and an in-house measure, respectively.

Results

Multi-group structured equation modeling revealed that family dysfunction was linked to internalizing and externalizing problems in OAD, but not controls, across time. Risk status did not moderate family dysfunction's mediation of the relationship between stressful life events and negative outcomes in adulthood.

Conclusions

OAD show high sensitivity to dysfunction in the rearing environment across childhood and adolescence, which supports the use of family based interventions to prevent the development of mental disorders in high-risk youth.

父母患有情感障碍的后代在整个成长过程中的家庭功能障碍、生活压力事件和心理健康问题
背景父母患有情感障碍(OAD),其子女有可能患上多种精神障碍。众所周知,养育环境的缺陷和高度压力是导致情感障碍后代出现不良后果的风险因素。在以往研究的基础上,我们旨在研究家庭功能障碍、生活压力事件与 OAD 和父母无情感障碍的对照组后代的心理健康之间的纵向关系。在本研究中,我们假设,与对照组相比,高水平的家庭功能障碍将与OAD在不同时期出现更多的内化和外化问题有关,而且家庭功能障碍将介导青少年时期的生活压力事件与成年后不良心理健康之间的关系,尤其是在OAD中。方法作为追踪青少年生活调查(TRAILS)的一部分,2230 名参与者(51% 为女性,基线年龄为 11.1 岁,标准差为 0.6)及其父母完成了横跨 15 年的六个时间点的测量。结果多组结构方程模型显示,在不同时期,家庭功能障碍与OAD的内化和外化问题有关,而与对照组无关。结论OAD在童年和青少年时期对抚养环境中的功能障碍表现出高度敏感性,这支持使用基于家庭的干预措施来预防高危青少年精神障碍的发展。
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来源期刊
CiteScore
13.80
自引率
5.30%
发文量
169
审稿时长
1 months
期刊介绍: The Journal of Child Psychology and Psychiatry (JCPP) is a highly regarded international publication that focuses on the fields of child and adolescent psychology and psychiatry. It is recognized for publishing top-tier, clinically relevant research across various disciplines related to these areas. JCPP has a broad global readership and covers a diverse range of topics, including: Epidemiology: Studies on the prevalence and distribution of mental health issues in children and adolescents. Diagnosis: Research on the identification and classification of childhood disorders. Treatments: Psychotherapeutic and psychopharmacological interventions for child and adolescent mental health. Behavior and Cognition: Studies on the behavioral and cognitive aspects of childhood disorders. Neuroscience and Neurobiology: Research on the neural and biological underpinnings of child mental health. Genetics: Genetic factors contributing to the development of childhood disorders. JCPP serves as a platform for integrating empirical research, clinical studies, and high-quality reviews from diverse perspectives, theoretical viewpoints, and disciplines. This interdisciplinary approach is a key feature of the journal, as it fosters a comprehensive understanding of child and adolescent mental health. The Journal of Child Psychology and Psychiatry is published 12 times a year and is affiliated with the Association for Child and Adolescent Mental Health (ACAMH), which supports the journal's mission to advance knowledge and practice in the field of child and adolescent mental health.
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