Matrix-assisted laser desorption/ionization mass spectrometry imaging for quorum sensing

IF 3.5 3区生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

AMB Express Pub Date : 2024-04-25 DOI:10.1186/s13568-024-01703-6

Christel Kuik, Sanne W.G. van Hoogstraten, Jacobus J.C. Arts, Maarten Honing, Berta Cillero-Pastor

引用次数: 0

Abstract

Quorum sensing (QS) is a complex communication system in bacteria, directing their response to the environment. QS is also one of the main regulators of bacterial biofilms’ formation, maturation and dispersion. Matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) is a molecular imaging technique that allows the mapping of QS molecules in bacterial biofilms. Here, we highlight the latest advances in MALDI-MSI in recent years and how this technology can improve QS understanding at the molecular level.

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用于法定人数感应的基质辅助激光解吸电离质谱成像技术

法定量感应（QS）是细菌体内一种复杂的通信系统，可引导细菌对环境做出反应。QS 也是细菌生物膜形成、成熟和分散的主要调节因素之一。基质辅助激光解吸电离（MALDI）质谱成像（MSI）是一种分子成像技术，可以绘制细菌生物膜中的 QS 分子图。在此，我们将重点介绍近年来 MALDI-MSI 的最新进展，以及该技术如何在分子水平上提高对 QS 的认识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

AMB Express BIOTECHNOLOGY & APPLIED MICROBIOLOGY-

CiteScore

7.20

自引率

2.70%

发文量

141

审稿时长

13 weeks

期刊介绍： AMB Express is a high quality journal that brings together research in the area of Applied and Industrial Microbiology with a particular interest in ''White Biotechnology'' and ''Red Biotechnology''. The emphasis is on processes employing microorganisms, eukaryotic cell cultures or enzymes for the biosynthesis, transformation and degradation of compounds. This includes fine and bulk chemicals, polymeric compounds and enzymes or other proteins. Downstream processes are also considered. Integrated processes combining biochemical and chemical processes are also published.