A CASE REPORT OF HENOCH-SCHÖNLEIN PURPURA

Raksha Kamat, Panna Bulsara
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Abstract

Background: Henoch-Schönlein purpura (HSP) is the most frequent leukocytoclastic systemic small-vessel vasculitis in children. HSP can present with a wide variety of clinical symptoms, from proteinuria and microscopic hematuria without any symptoms to variable degrees of acute kidney injury (AKI) and fast progressing glomerulonephritis with a high risk of long-term renal impairment. The kind and extent of organ involvement determines therapy options in more severe situations. A 12 year old Case Summary: female admitted to New Civil Hospital Surat with chief complaints of rash since 8 days. Also associated with joint and abdominal pain. Patient also gave history of cough, cold, sorethroat. Investigations done, Dermatologist opinion was taken for skin biopsy, skin biopsy showed leukocytoclastic vasculitis with IgA deposits. Patient Started on prednisolone 1mg/kg/day, Patient showed improvement with prednisolone within one week and was discharged sucessfully. It is crucial to dene the differential diagnosis w Discussion: ith other bullous diseases in childhood. Prognosis of HSP is good if there is no renal involvement. Henoch-Schönlein purpura is a Conclusion: frequent paediatric vasculitis that is multi-systemic. Although the prognosis is often quite good, some individuals may experience long-term effects, usually in the kidneys.
一例亨诺克-舍恩莱因紫癜病例报告
背景:过敏性紫癜(HSP)是儿童中最常见的白细胞破坏性全身性小血管炎。HSP 可表现出多种临床症状,从无任何症状的蛋白尿和镜下血尿,到不同程度的急性肾损伤(AKI)和进展迅速的肾小球肾炎,以及长期肾功能损害的高风险。器官受累的种类和程度决定了更严重情况下的治疗方案。病例摘要:女性,12 岁,主诉皮疹 8 天,入住苏拉特新民事医院。同时伴有关节和腹痛。患者也有咳嗽、感冒和喉咙痛病史。皮肤科医生建议患者进行皮肤活检,活检结果显示患者患有白细胞减少性血管炎,并伴有 IgA 沉积。患者开始服用泼尼松龙 1 毫克/千克/天,一周后病情有所好转并顺利出院。讨论:与其他牛皮癣的鉴别诊断至关重要。如果没有累及肾脏,HSP的预后良好。结论:HSP 是一种多系统的小儿血管炎。虽然预后通常很好,但有些人可能会受到长期影响,通常是肾脏。
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