Orthotopic Robot-assisted Kidney Transplantation: Surgical Technique and Preliminary Results

IF 25.3 1区 医学 Q1 UROLOGY & NEPHROLOGY
Francesc Vigués , Begoña Etcheverry , José I. Perez Reggeti , Josep Maria Gaya , Angelo Territo , Andrea Gallioli , Camille Berquin , Giuseppe Basile , José F. Suárez , Maria Fiol , Oscar Buisan , Lluís Riera , Thomas Prudhomme , Nicolas Doumerc , Alessio Pecoraro , Alberto Breda , European Association of Urology Robotic Urology Section Robot-assisted Kidney Transplantation Working Group
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引用次数: 0

Abstract

Background and objective

Orthotopic kidney transplantation (KT) has been proposed as an option for patients ineligible for heterotopic KT. In this scenario, orthotopic robot-assisted KT (oRAKT) represents a novel, minimally invasive alternative to the open approach. Here we describe the largest oRAKT series of patients, with a focus on the surgical technique, perioperative surgical outcomes, and functional results.

Methods

We queried prospectively maintained databases from three referral centers to identify patients who underwent oRAKT and evaluated surgical and functional outcomes.

Key findings and limitations

Overall, 16 oRAKT procedures were performed between January 2020 and August 2023. These involved four donors after cardiovascular death, five donors after brain death, and seven living donors. All oRAKT procedures were carried out in the left renal fossa. The indication for oRAKT was extensive calcification of the external iliac vessels (100%), frequently associated with prior KT (31%). The median operative time was 295 min (interquartile range [IQR] 268–360) and the median rewarming time 48 min (IQR 40–54). Conversion to open surgery occurred in two cases (12%), and delayed graft function was observed in two cases (12%). Postoperative complications occurred in 11 patients (69%) and three (18%) experienced Clavien-Dindo grade >II complications. At median follow-up of 9 mo (IQR 7–17), 14 patients had a functioning graft and median creatinine of 1.49 mg/dl (IQR 1.36–1.72).

Conclusions and clinical implications

Although oRAKT is a challenging procedure, it represents a feasible option for individuals ineligible for heterotopic KT and yields favorable perioperative and mid-term functional outcomes.

Patient summary

We evaluated outcomes of orthotopic robot-assisted kidney transplantation (KT), in which the native kidney is removed and the donor kidney is transplanted into its place, in patients who are not eligible for heterotopic KT, in which the native kidney is left in place and the donor kidney is transplanted into a new location. We found that robot-assisted surgery is a safe and feasible alternative to traditional open surgery for orthotopic KT.

正位机器人辅助肾脏移植手术:手术技术和初步结果。
背景和目的异位肾移植(KT)已被提出作为不符合异位肾移植条件的患者的一种选择。在这种情况下,正位机器人辅助肾移植(orotopic robot-assisted KT,简称 oRAKT)是开放式方法的一种新型微创替代方法。方法我们查询了三个转诊中心的前瞻性数据库,确定了接受 oRAKT 的患者,并评估了手术和功能结果。主要发现和局限性2020 年 1 月至 2023 年 8 月期间,共进行了 16 例 oRAKT 手术。这些手术涉及 4 名心血管死亡供体、5 名脑死亡供体和 7 名活体供体。所有 oRAKT 手术均在左肾窝进行。oRAKT 的适应症是髂外血管广泛钙化(100%),通常与之前的 KT(31%)有关。手术时间中位数为295分钟(四分位数间距[IQR] 268-360),复温时间中位数为48分钟(IQR 40-54)。两例患者(12%)转为开放手术,两例患者(12%)出现移植物功能延迟。11 例患者(69%)出现术后并发症,3 例(18%)出现 Clavien-Dindo II 级并发症。中位随访 9 个月(IQR 7-17)时,14 例患者的移植物功能正常,中位肌酐为 1.49 mg/dl (IQR 1.36-1.72)。患者摘要我们对不符合异位肾移植条件的患者进行了正位机器人辅助肾移植(KT)的疗效评估,在异位肾移植中,原位肾脏被切除,供肾被移植到原位肾脏的位置;在正位机器人辅助肾移植中,原位肾脏被保留,供肾被移植到一个新的位置。我们发现,与传统的开放式手术相比,机器人辅助手术是一种安全可行的正位 KT 替代方案。
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来源期刊
European urology
European urology 医学-泌尿学与肾脏学
CiteScore
43.00
自引率
2.60%
发文量
1753
审稿时长
23 days
期刊介绍: European Urology is a peer-reviewed journal that publishes original articles and reviews on a broad spectrum of urological issues. Covering topics such as oncology, impotence, infertility, pediatrics, lithiasis and endourology, the journal also highlights recent advances in techniques, instrumentation, surgery, and pediatric urology. This comprehensive approach provides readers with an in-depth guide to international developments in urology.
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