J.A. Albarracin Duarte , J. Chaparro Hernández , J.A. Rojas Aceros , J.E. Valoyes Gélvez , J. Ascuntar , F. Jaimes
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Abstract
Objective
To identify the first symptoms and signs of patients with suspected infection or sepsis and their association with the composite outcome of admission to the Intensive Care Unit (ICU) or mortality.
Design
Prospective cohort study between June 2019 and March 2020.
Setting
Hospital Universitario San Vicente Fundación, Colombia.
Patients
Over 18 years of age with suspicion or confirmation of sepsis, which required hospitalization.
Interventions
None.
Main variables of interest
Symptoms and signs associated with infection, with their time of evolution, specified in the study.
Results
From 1005 eligible patients, 261 were included. After multivariable adjustment with a logistic regression model, the main factors for ICU admission or mortality were heart rate (OR 1.04 with 95% CI 1.04–3.7), respiratory rate (OR 1.19 with 95% CI 1.0−1.4) and capillary refill time (OR 3.4 with 95% CI 1.9−6.1).
Conclusions
Heart rate, respiratory rate, and capillary refill may behave as early predictors of ICU admission and mortality in cases of sepsis.
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