Debunking the idea of biological optimisation: quantitative biology to the rescue

Abstract

The idea that plants would be efficient, frugal or optimised echoes the recurrent semantics of ‘blueprint’ and ‘program’ in molecular genetics. However, when analysing plants with quantitative approaches and systems thinking, we instead find that plants are the results of stochastic processes with many inefficiencies, incoherence or delays fuelling their robustness. If one had to highlight the main value of quantitative biology, this could be it: plants are robust systems because they are not efficient. Such systemic insights extend to the way we conduct plant research and opens plant science publication to a much broader framework.