Zoonotic bacteria in the vicinity of animal farms as a factor disturbing the human microbiome: a review.

IF 1.4 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International journal of occupational medicine and environmental health Pub Date : 2024-04-04 DOI:10.13075/ijomeh.1896.02003

A. Kozajda, Emilia Miśkiewicz, Karolina Jeżak

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引用次数: 0

Abstract

This review is aimed at summarizing the current state of knowledge about the relationship between environmental exposure to the bioaerosol emitted by intensive livestock farming and changes in the microbiome of people living in livestock farm vicinity. The PubMed, Scopus and Web of Science databases were searched by crossing keywords from the following 3 groups: a) "livestock," "animal farms," "animal breeding"; b) "microbiome," "resistome"; c) "livestock vicinity," "farm vicinity," "neighborhoods and health" in 2010-2022. Literature screening did not reveal any paper related to the full microbiome composition in the population studied. In the study, the authors included 7 papers (5 from the Netherlands, 1 from the USA, and 1 from China). The studies confirmed the carriage of Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), livestockassociated MRSA (LA-MRSA MC398) and multidrug-resistant S. aureus (MDRSA) in the nasal microbiome of adults and children living within 500-2000 m from a livestock farm. Clostridium difficile, including LA-ribotype RT078 carriage, was detected in the intestinal microbiome of adults living within 500-1000 m. Extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae were confirmed in the intestinal microbiome of adults living within 500-6200 m. Knowledge on the composition of the microflora of people living in livestock farm vicinity is insufficient to conclude about changes in the microbiome caused by the environmental emission of bioaerosol. The carriage prevalence of the LA-bacteria, including both strains with antimicrobial resistance and antimicrobial resistance genes, confirms the presence of zoonotic bacteria in the human microflora in populations without occupational contact with animals. It cannot be ruled out that zoonotic bacteria, as a component of the microbiome, have a negative impact on people's health. Int J Occup Med Environ Health. 2024;37(2).

查看原文本刊更多论文

动物养殖场附近的人畜共患细菌是干扰人类微生物组的一个因素：综述。

本综述旨在总结有关环境暴露于集约化畜牧业排放的生物气溶胶与畜牧场附近居民微生物组变化之间关系的知识现状。通过交叉以下三组关键词在 PubMed、Scopus 和 Web of Science 数据库中进行了检索：a) "牲畜"、"畜牧场"、"动物饲养"；b) "微生物组"、"抗性组"；c) "畜牧场附近"、"农场附近"、"邻里与健康"（2010-2022 年）。通过文献筛选，没有发现任何与所研究人群的全部微生物组组成相关的论文。在这项研究中，作者收录了 7 篇论文（5 篇来自荷兰，1 篇来自美国，1 篇来自中国）。这些研究证实，生活在距离畜牧场 500-2000 米范围内的成人和儿童的鼻腔微生物组中携带金黄色葡萄球菌，包括耐甲氧西林金黄色葡萄球菌（MRSA）、家畜相关 MRSA（LA-MRSA MC398）和耐多药金黄色葡萄球菌（MDRSA）。生活在距离畜牧场 500-1000 米范围内的成人的肠道微生物群中检测到艰难梭菌，包括携带的 LA-ribotype RT078。LA 细菌（包括具有抗菌药耐药性和抗菌药耐药性基因的菌株）的携带率证实，在与动物没有职业接触的人群中，人畜共患病细菌存在于人体微生物区系中。不排除人畜共患病细菌作为微生物组的一个组成部分，会对人类健康产生负面影响。Int J Occup Med Environ Health.2024;37(2).

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来源期刊

International journal of occupational medicine and environmental health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.40

自引率

5.00%

发文量

审稿时长

7.5 months

期刊介绍： The Journal is dedicated to present the contemporary research in occupational and environmental health from all over the world. It publishes works concerning: occupational and environmental: medicine, epidemiology, hygiene and toxicology; work physiology and ergonomics, musculoskeletal problems; psychosocial factors at work, work-related mental problems, aging, work ability and return to work; working hours, shift work; reproductive factors and endocrine disruptors; radiation, ionizing and non-ionizing health effects; agricultural hazards; work safety and injury and occupational health service; climate change and its effects on health; omics, genetics and epigenetics in occupational and environmental health; health effects of exposure to nanoparticles and nanotechnology products; human biomarkers in occupational and environmental health, intervention studies, clinical sciences’ achievements with potential to improve occupational and environmental health.