Eruptive Nevus Following Rituximab Treatment: Unusual Dermoscopic Presentation: A Case Report

Abstract

Background: Eruptive nevi can occur following various conditions, including the use of immunosuppressive and immunomodulatory drugs such as biologics. Dermoscopy typically reveals a pattern of brown globules arranged in a ring at the periphery. We report a case of eruptive nevus with an atypical dermoscopic pattern in a patient receiving Rituximab. Observation: A 37-year-old female patient, followed for acquired bullous epidermolysis, developed pigmented and extensive macules six months later. Dermoscopy of a lesion on the trunk, which was increasing in size, showed a homogeneous brown pattern with irregularly arranged brown globules and dots at the center and periphery. Biopsy revealed a junctional nevus. Conclusion: The atypical brown pattern on dermoscopy of eruptive nevi is described for the first time, particularly after rituximab therapy.